SKU: 97465338004

Periostin Recombinant Rabbit mAb (S-2824-17)

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Description

Periostin Recombinant Rabbit mAb (S-2824-17)Product Specification Host Rabbit Antigen Periostin Synonyms PN; Osteoblast specific factor 2 (OSF 2); OSF2; POSTN Immunogen Recombinant Protein Location Secreted Accession Q15063 Clone Number S 2824 17 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Positive Sample NCI H69 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0.

Product Specification


Host Rabbit
Antigen Periostin
Synonyms PN; Osteoblast-specific factor 2 (OSF-2); OSF2; POSTN
Immunogen Recombinant Protein
Location Secreted
Accession Q15063
Clone Number S-2824-17
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IHC-P
Reactivity Hu
Positive Sample NCI-H69
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu
IHC-P 1:2000 Hu

Background

Periostin is a 90-kDa secreted matricellular protein that consists of a typical signal peptide, an EMI domain, four tandem fasciclin-1 (FAS-1) domains implicated in cell adhesion and protein–protein interactions, and a C-terminal splice variant-rich domain that can generate six isoforms; it is predominantly expressed in collagen-rich connective tissues such as periodontal ligament, periosteum, heart valves, skin, and fibrotic lesions, where it is rapidly induced by TGF-β, IL-4/IL-13, mechanical stress or hypoxia and then deposited into the extracellular matrix via integrin-mediated binding to αvβ3, αvβ5 or α6β4 receptors on fibroblasts, thereby promoting collagen fibrillogenesis, cross-linking and tissue remodeling during embryonic development, wound healing, bone fracture repair, cardiac remodeling after myocardial infarction, and pathological fibrosis in asthma, atopic dermatitis, liver cirrhosis and various solid tumors, while also activating PI3K/Akt, FAK/Src, ERK and YAP/TAZ signaling pathways that enhance epithelial–mesenchymal transition, angiogenesis, cancer cell invasion, metastatic niche formation and chemoresistance, making it a valuable biomarker for disease progression and a potential therapeutic target for fibrosis and cancer.

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SKU: 97465338004

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Reviewed in the United States on April 25, 2026
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Reviewed in the United States on May 29, 2026
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Boise, US
★★★★★ 5
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Reviewed in the United States on March 28, 2026
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Super cute and comfy sandals! I love that they are adjustable.
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Reviewed in the United States on May 26, 2026
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Nathaniel
Louisville, US
★★★★★ 5
Stylish comfort you can wear all day!
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My wife has been been wearing the UGG Goldenstar Sandals for a few weeks now, and they’ve totally exceeded expectations. These sandals strike the perfect balance between comfort and style, and she’s gotten so many compliments on them! Pros: • Super Comfortable: The cushioned footbed feels like walking on clouds. Perfect for long days on your feet or casual outings. • Lightweight: Unlike some chunky sandals, these are surprisingly light but still feel supportive and well-made. • Adjustable Straps: The Velcro straps make it easy to get the perfect fit, and they’re great for swelling feet after a long day. • Versatile Style: They look great with everything—from jeans and shorts to casual dresses. • High-Quality Materials: Typical UGG quality—durable suede and solid construction. Cons: • Suede Requires Care: The upper is suede, so they’re not ideal for wet conditions and do need a bit of maintenance to keep looking fresh. • Pricey: They’re on the higher end cost-wise, but I’d say the comfort and quality justify the price. I’m really happy with these sandals. They’re a perfect mix of fashion and function, and I’d definitely buy them again in another color!
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Reviewed in the United States on April 9, 2025

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