SKU: 90799566200

Lymphocyte antigen 75/CD205 Recombinant Rabbit mAb (S-2707-25)

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Description

Lymphocyte antigen 75/CD205 Recombinant Rabbit mAb (S-2707-25)Product Specification Host Rabbit Antigen CD205 Synonyms Lymphocyte antigen 75; Ly 75; C type lectin domain family 13 member B; DEC 205; gp200 MR6; CLEC13B; LY75 Immunogen Recombinant Protein Location Membrane Accession O60449 Clone Number S 2707 25 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Positive Sample THP 1, Daudi Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance

Product Specification


Host Rabbit
Antigen CD205
Synonyms Lymphocyte antigen 75; Ly-75; C-type lectin domain family 13 member B; DEC-205; gp200-MR6; CLEC13B; LY75
Immunogen Recombinant Protein
Location Membrane
Accession O60449
Clone Number S-2707-25
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IHC-P
Reactivity Hu
Positive Sample THP-1, Daudi
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu
IHC-P 1:1000 Hu

Background

CD205, also known as DEC205 or LY75, is a ~205 kDa type I transmembrane glycoprotein belonging to the macrophage mannose receptor family of C-type lectins; it contains an N-terminal cysteine-rich domain, a fibronectin type II repeat, ten tandem C-type lectin-like carbohydrate-recognition domains, a single transmembrane segment and a short cytoplasmic tail harboring the tyrosine-based “FERN” and “DIEEV” endosomal sorting motifs that drive constitutive clathrin-mediated internalization and recycling to late endosomes/MHC class II compartments. Predominantly expressed on CD8α⁺ dendritic cells, thymic epithelial cells and certain B subsets, CD205 functions as a pattern-recognition receptor that binds apoptotic/necrotic cells, selected glycoproteins and CpG-rich nucleic acids, enabling efficient capture, processing and cross-presentation of antigens for initiation of CD8⁺ T-cell immunity; this property has made it a premier target for receptor-directed vaccination strategies in which antigens are fused to anti-CD205 antibodies to elicit potent, antigen-specific tolerance or protective responses. In addition, CD205 participates in peripheral T-cell deletion, central tolerance through negative selection in the thymus, and has been implicated in autoimmune diseases, tumor immunosurveillance and metastasis, with its expression levels correlating with prognosis in several cancers, thereby serving as both a biomarker and a therapeutic gateway in immunotherapy.

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Exchange/Return Notes
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SKU: 90799566200

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4.4 ★★★★★
Based on 11 reviews
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Christine Boyd George
Whiting, US
★★★★★ 5
I use this every day on my face and body
I have this in my subscriptions because it works so well and makes my skin feel so soft. It's a very good quality product but it is whipped. I didn't know that till it first came
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 20, 2026
G
Verified Purchase
g4golf
Massapequa, US
★★★★★ 3
Temus has better beef tallow skin cream..
* Got much better results from a temu beef tallow/manuka honey skin cream... the temu one is creamer and less dense, so it spread and immediate melts/absorbs right into your skin... next morning results much better in temu product.. ama,ons is pasty and greasey, doesn't absorb like the temu one... doesn't feel good on skin... temu soaks right up into your skin like a sponge.. no greasy feel... just smooth skin... i ordered temu's again...
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Reviewed in the United States on May 24, 2026
R
Verified Purchase
Renee
Massapequa, US
★★★★★ 5
Amazing!
Scent: Unscented, Size: 8 Ounce (Pack of 1), Scent: Unscented, Size: 8 Ounce (Pack of 1)
I’ve been using this for a few days now and my skin has already improved so much!! My skin feels sooo much smoother, especially in the areas where my dry spots were really showing. This tallow helped smooth everything out and absorbed into my skin amazingly. I honestly have nothing but good things to say about this product. I also love that it comes in a big jar because I use moisturizer 24/7, so this will definitely last me a while. It’s been especially amazing for my eczema it cleared up within just a few days! I will forever repurchase this and recommend it to everyone. There’s no fragrance, which I love. It does feel a little greasy at first, but that goes away pretty quickly once it absorbs. The application, size, and absorption are all amazing 💕
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 26, 2026
L
Verified Purchase
Luz Lopez
Phoenix, US
★★★★★ 5
very amazing product
Scent: Unscented, Size: 8 Ounce (Pack of 1), Scent: Unscented, Size: 8 Ounce (Pack of 1)
i love this product. it’s very smooth and buttery. no scent and truly good for skin.
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Reviewed in the United States on May 25, 2026
M
Verified Purchase
MC
Natrona Heights, US
★★★★★ 4
Not bad for the price point.
Scent: Unscented, Size: 8 Ounce (Pack of 1)
I don't mind this product; it's well-priced; however, in practice, it was slightly too oily. I prefer other beef tallow products, or even just straight-up beef tallow, rather than this product. Because I have severe eczema on my hands, I prefer tallow blends that have faster absorption. However, this product is perfectly suited for use as a night moisturizer or as a hand mask. I would probably buy this again if the formulation were less oily/greasy next time.
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Reviewed in the United States on May 30, 2026

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