SKU: 93602446409

GIPR Fc Chimera Protein, Human

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Description

GIPR Fc Chimera Protein, HumanProduct Specification Species Human Accession P48546 1 Amino Acid Sequence Arg22 Gln138, with C terminal Human IgG Fc

Product Specification


Species Human
Accession P48546-1
Amino Acid Sequence Arg22-Gln138, with C-terminal Human IgG Fc RAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
Expression System HEK293
Molecular Weight 45-54kDa (Reducing)
Purity

>95% by SDS-PAGE

Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag Human Fc Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

Background

Glucose-dependent insulinotropic polypeptide receptor (GIPR) are G protein-coupled receptors belonging to the secretin receptor super-family, also known as class B1. GIPR comprises an N-terminal extracellular domain (ECD), a central domain consisting of seven transmembrane α-helices, and a C-terminal, cytoplasmic domain that mediates intracellular signal transduction by physical association with the G protein. GIPR increases insulin secretion in hyperglycemia and stimulates glucagon release in hypoglycemia. It also plays an important role in adipogenesis, islet β cell proliferation and insulin release, and is associated with type 2 diabetes, obesity and neurodegenerative diseases.

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Exchange/Return Notes
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SKU: 93602446409

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4.8 ★★★★★
Based on 25 reviews
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Product Reviews
K
Verified Purchase
Kindle Customer
Louisville, US
★★★★★ 5
Heals chapped, dry lips Fast
Amazing restorative lip balm. Dry, chapped lips healed in a few hours!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 23, 2026
K
Verified Purchase
Kelly C.
Carnegie, US
★★★★★ 5
The best lip balm!
I’m so addicted to this lip balm!!! If you have secret chapped lips this will fix it in a day or two!!! And even if u don’t, it keeps your lips soooo soft!!! A bit pricey but it goes on sale a lot so watch for that.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 10, 2025
L
Verified Purchase
Laureleaves
Battle Creek, US
★★★★★ 4
Amazing product but star down on price
I desperately needed a healing lip balm for my perpetually chapped and scarred lips, and at first was skeptical that this was nothing but a glorified aquaphor, which works well enough for me but I was curious about better treatments. After some weeks of regular use, my lips feel incredible. I am sold. I only wish two things: that it was a smidgen cheaper, and that there was a version with SPF so I could have one to wear out during the day and have it’s magic working all the time.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 25, 2024
L
Verified Purchase
LA and BM
Natrona Heights, US
★★★★★ 5
Fantastic for rosacea, PD, atopic dermatitis, dry skin
I’ve been using this for close to a year and it is amazing for my super sensitive and dry skin. I have perioral dermatitis, atopic dermatitis, and rosacea and live in Minnesota with bitter cold and the heater running over half the year. Cicalfate cream doesn’t flare any of these and it helps reduce redness and completely resolves dry skin. I use about a pea size amount AM and PM,, apply to dry skin, massage in, then mist with the Avene thermal water spray. Although the cream is thick, the slight white cast absorbs within a few minutes. I do not wear foundation so I don’t know how this affects it.it doesn’t burn my eyes and I’m a contact lens wearer. A big tube of cream lasts me the better part of a year.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 28, 2025
P
Verified Purchase
P. Lau
Houston, US
★★★★★ 5
Great for harsh winters
I was recommended this product by ChatGPT as an effective and safe product that my wife (who is currently nursing) can use. We have been very mindful of certain additives and chemicals in our products and this was able to meet our requirements. Separately in the harsh winter in the northeast, this has been extremely effective in protecting the lips
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Reviewed in the United States on January 29, 2026

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