SKU: 82339073375

MMP-8 His Tag Protein, Human

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Description

MMP-8 His Tag Protein, HumanProduct Specification Species Human Synonyms MMP 8, CLG1, HNC, PMNL CL Accession P22894 Amino Acid Sequence Phe21 Gly467, with C terminal His Expression System HEK293 Molecular Weight 65 75kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation.

Product Specification


Species Human
Synonyms MMP-8, CLG1, HNC, PMNL-CL
Accession P22894
Amino Acid Sequence Phe21-Gly467, with C-terminal His
Expression System HEK293
Molecular Weight 65-75kDa
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Hasty K A. et al. (1990) Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases. J. Biol. Chem. 265: 11421-11424.

2、Blaeser J. et al. (1991) Mercurial activation of human polymorphonuclear leucocyte procollagenase. Eur. J. Biochem. 202: 1223-1230.

Background

A protease is an enzyme with a proteolytic activity that facilitates the digestion of its substrates. Membrane-type I matrix metalloproteinase (MT1-MMP), a member of the broader matrix metalloproteinases (MMP) family, is involved in the regulation of diverse cellular activities. Parasite-derived products have been shown to regulate host matrix metalloproteinases (MMPs), contributing to CE pathogenesis and progressive liver fibrosis in intermediate hosts. The current study aimed to investigate the potential role of MMP1, 7, 8, and 13 in E. granulosus induced liver fibrosis.MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumor may have a protective effect against lymph node metastasis.
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SKU: 82339073375

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Reviewed in the United States on February 21, 2026
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Reviewed in the United States on August 31, 2025
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Monique & family account
Los Angeles, US
★★★★★ 1
BUYER BEWARE NOT A AUTHORIZED EPSON SELLER & YOU CANNOT REG THIS PRINTER
I purchased the Epson SureColor F170 from 6Ave through Amazon and discovered during setup that I could not register the printer with Epson. After contacting Epson customer support, I was informed that 6Ave is not an authorized Epson reseller for this product. That the serial number was invalid and likely from overseas. When I had been trying it I got "INVALID SERIAL NUMBER" and when I thought maybe the 0 was an O I got a message that it had already been registered. As a result, Epson would not allow me to register the printer, which raises concerns about warranty coverage and access to manufacturer support. Had this been disclosed before purchase, I would have purchased from an authorized dealer instead. Consumers should be clearly informed when a seller is not authorized by the manufacturer, especially for a product that represents a significant investment. Very disappointing experience. I am glad I was able to contact Amazon and report them.
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Reviewed in the United States on June 6, 2026
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Luz Marina Amaya
Charlottesville, US
★★★★★ 5
Entrega rapidisima
La envié a Venezuela. Me dijeron que funciona bien
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Reviewed in the United States on June 10, 2026
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shawn
Chelsea, US
★★★★★ 1
Buyer Beware: Not an Authorized Epson Reseller
I purchased an Epson SureColor F170 from 6Ave through Amazon and discovered during setup that I could not register the printer with Epson. After contacting Epson customer support, I was informed that 6Ave is not an authorized Epson reseller for this product. As a result, Epson would not allow me to register the printer, which raises concerns about warranty coverage and access to manufacturer support. Had this been disclosed before purchase, I would have purchased from an authorized dealer instead. Consumers should be clearly informed when a seller is not authorized by the manufacturer, especially for a product that represents a significant investment. Very disappointing experience.
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Reviewed in the United States on May 29, 2026

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