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Description
LYPD8 Fc Chimera Protein, HumanProduct Specification Species Human Synonyms LYPD8, LY6, PLAUR domain containing 8 Accession Q6UX82 Amino Acid Sequence Leu20 Asn215, with C terminal Human IgG1 Fc
Product Specification
| Species | Human |
| Synonyms | LYPD8, LY6, PLAUR domain containing 8 |
| Accession | Q6UX82 |
| Amino Acid Sequence | Leu20-Asn215, with C-terminal Human IgG1 Fc LSCVQCNSWEKSCVNSIASECPSHANTSCISSSASSSLETPVRLYQNMFCSAENCSEETHITAFTVHVSAEEHFHFVSQCCQGKECSNTSDALDPPLKNVSSNAECPACYESNGTSCHGKPWKCYEEEQCVFLVAELKNDIESKSLVLKGCSNVSNATCQFLSGENKTLGGVIFRKFECANVNSLTPTSAPTTSHNIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Expression System | HEK293 |
| Molecular Weight | 60-95kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human Fc Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Okumura R. et al. (2020) Lypd8 inhibits attachment of pathogenic bacteria to colonic epithelia. Mucosal Immunol. 13: 75-85. |
Background
Lypd8 is a highly N-glycosylated glycosylphosphatidylinositol-anchored protein that is highly expressed on colonic IECs and constitutively shed into the intestinal lumen. Lypd8 inhibits the invasion of colonic epithelia by flagellated commensal bacteria such as Proteus mirabilis and E. coli belonging to Enterobacteriaceae family by suppressing their motility via flagella binding. However, it remains unclear whether Lypd8 has a protective function against pathogenic bacteria, including pathogenic E. coli, Salmonella, Shigella, and Citrobacter, many of which belong to the family Enterobacteriaceae.
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4.6 ★★★★★
Based on 5 reviews
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Product Reviews
★★★★★ 5
Comodos
Size: 5, Color: (002) Black/Black/Anthracite
Que zapatos mas suaves por el precio me encantaron mas
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 31, 2026
★★★★★ 5
Under Armour never disappoints
Size: One Size Fits Most, Color: (001) Black / / White
Great waist bag that makes traveling more enjoyable and fun. It's width with compartments provides extra space for sorting out accessories
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Reviewed in the United States on June 7, 2026
★★★★★ 5
Lightweight and practical for carrying just the essentials
Size: One Size Fits Most, Color: (001) Black / / White
This waist bag is super practical and lightweight, perfect for days when I don’t want to carry a full purse. The fabric feels sturdy and the zipper works smoothly, nothing cheap or flimsy. It actually fits more than it looks phone, keys, lip balm, small wallet all organized without feeling bulky.
The strap adjusts well and stays in place, and it’s comfortable to wear crossbody or around the waist. It’s definitely more for essentials than for carrying a lot, but for quick errands, walks, gym or travel it’s perfect. Clean design, good quality, and easy to match with any outfit.
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Reviewed in the United States on December 7, 2025
★★★★★ 5
Great Bag
Size: One Size Fits Most, Color: (025) Castlerock / Black / Black
Plenty of space even for my book on the plane. No more need for a personal item. I will say that I made the mistake of hanging my hands on the belt bag and tweaked the muscles in my neck from that. Great durable back though. I paid around $20-25
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Reviewed in the United States on July 21, 2025
★★★★★ 5
Lots of room
Size: One Size Fits Most, Color: (001) Black / / White
This bag has more room than you would think, for something smaller.
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Reviewed in the United States on May 4, 2026