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Description
B7-H7/HHLA2 His Tag Protein, HumanProduct Specification Species Human Synonyms B7 H7, HHLA2, B7 Homolog 7 Accession Q9UM44 Amino Acid Sequence Ile23 Asn344, with C terminal 8*His
Product Specification
| Species | Human |
| Synonyms | B7-H7, HHLA2, B7 Homolog 7 |
| Accession | Q9UM44 |
| Amino Acid Sequence | Ile23-Asn344, with C-terminal 8*His IFPLAFFIYVPMNEQIVIGRLDEDIILPSSFERGSEVVIHWKYQDSYKVHSYYKGSDHLESQDPRYANRTSLFYNEIQNGNASLFFRRVSLLDEGIYTCYVGTAIQVITNKVVLKVGVFLTPVMKYEKRNTNSFLICSVLSVYPRPIITWKMDNTPISENNMEETGSLDSFSINSPLNITGSNSSYECTIENSLLKQTWTGRWTMKDGLHKMQSEHVSLSCQPVNDYFSPNQDFKVTWSRMKSGTFSVLAYYLSSSQNTIINESRFSWNKELINQSDFSMNLMDLNLSDSGEYLCNISSDEYTLLTIHTVHVEPSQETASHNGGGSHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 51-67kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Zhu Y. et al. (2013) B7-H5 costimulates human T cells via CD28H. Nat Commun. 4: 2043. 2、Dong Z. et al. (2018) EGFR may participate in immune evasion through regulation of B7-H5 expression in non-small cell lung carcinoma. Mol Med Rep. 18: 3769-3779. |
Background
Human endogenous retrovirus-H long terminal repeat-associating protein 2 (HHLA2; also known as B7H7 or B7H5) is the only member of the B7 protein family found in humans. HHLA2 cannot be found in mice and is mainly expressed in human breast, lung, thyroid, melanoma, pancreas, ovary, liver, bladder, colon, prostate, kidney and esophagus cancer cells, activated myeloid cells, monocyte-derived macrophages and dendritic cells. In addition, HHLA2 interacts with the co-receptor CD28H to stimulate T cell proliferation, differentiation and the production of cytokines, including IFN-γ, IL-2 and IL-10. In terms of cancer, higher expression levels of HHLA2 were previously reported to be associated with poorer prognoses or higher degrees of tumour invasion in lung carcinoma, hepatocellular carcinoma and prostate cancer.
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4.1 ★★★★★
Based on 9 reviews
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Product Reviews
★★★★★ 5
Buenas
Color: White, Size: 4 Panel Basic
Utilizamos estas divisiones por largo tiempo y las tiramos enteras y en perfecto estado . Muy buenas
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Reviewed in the United States on May 21, 2026
★★★★★ 5
Excellent room divider
Color: Black, Size: 8 Panel
I have three of these from this company! 2 of them are 6 panel and one 8 panel (this one). A+ quality and wonderful with privacy. I have this on my screened in balcony and it withstands the wind pretty well. Fits right behind my giant plant pots. No assembly needed and it was long enough to cover the entire screened area. No more nosy neighbors! Great for
Condos! Woohoo!
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Reviewed in the United States on May 17, 2026
★★★★★ 5
Awesome privacy
Color: Charcoal Gray, Size: 8 Panel
Awesome for around the pool for a little privacy this summer very durable construction well made
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Reviewed in the United States on April 26, 2026
★★★★★ 5
Great Divider
Comes assembled. It is heavy, but fairly easy to move and use. I’m 5’4, 110 and I can do it myself. It’s thick, it’s tall, it looks good, not sloppy or cheap. Doesn’t smell. Great room divider. We use it for our office between our desks.
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Reviewed in the United States on September 27, 2025
★★★★★ 5
Good purchase
Color: White, Size: 8 Panel
I bought this in white for use in a finished basement to hide equipment on the wall and create a nice space to place a bed. Because it doesn’t need to be moved and the room is temperature controlled, I expect it to last for a long time. The screen is pretty and I like that the woven material is not easily breakable. I’m pleased with the purchase.
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Reviewed in the United States on September 26, 2025