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Description
NUT Recombinant Rabbit mAb (SDT-3062)Product Specification Host Rabbit Antigen NUT Synonyms NUT family member 1; Nuclear protein in testis; C15orf55; NUTM1 Location Cytoplasm, Nucleus Accession Q86Y26 Clone Number SDT 3062 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IF Reactivity Hu, Rt Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability &
Product Specification
| Host | Rabbit |
| Antigen | NUT |
| Synonyms | NUT family member 1; Nuclear protein in testis; C15orf55; NUTM1 |
| Location | Cytoplasm, Nucleus |
| Accession | Q86Y26 |
| Clone Number | SDT-3062 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IF |
| Reactivity | Hu, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Rt |
| IHC-P | 1:250 | Hu, Rt |
| IF | 1:500 | Hu, Rt |
Background
The NUT protein, which stands for nuclear protein in testis, is a transcription factor that plays a crucial role in embryonic development. It is typically found in the testes and is involved in the regulation of gene expression. However, when it is abnormally expressed or translocated in other tissues, it can lead to the development of certain types of cancers, particularly NUT midline carcinoma (NMC), a rare but aggressive malignancy. The presence of the NUT protein in cancer cells is often associated with poor prognosis, and it has become an important target for research in cancer diagnostics and therapeutics.
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