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Description
Human MCP-1 OneStep ELISA KitProduct Specification Antigen MCP 1 Immunogen Recombinant Protein Antibody Type Recombinant mAb Reactivity Hu Purification Protein A Stability & Storage 12 months from date of receipt reconstitution, 2 to 8'C as supplied. Kit Precision Intra assay: 2. 8% Inter assay: 3. 7% Sample type Cell culture supernatant, Serum,Plasma Assay type Sandwich (quantitative) Sensitivity 0. 716 pg ml Range 1. 56 pg mL 100 pg mL Recovery Cell culture supernatant: 101%
Product Specification
| Antigen | MCP-1 |
| Immunogen | Recombinant Protein |
| Antibody Type | Recombinant mAb |
| Reactivity | Hu |
| Purification | Protein A |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8'C as supplied. |
Kit
| Precision | Intra-assay: 2.8%； Inter-assay: 3.7% |
| Sample type | Cell culture supernatant, Serum,Plasma |
| Assay type | Sandwich (quantitative) |
| Sensitivity | 0.716 pg/ml |
| Range | 1.56 pg/mL – 100 pg/mL |
| Recovery | Cell culture supernatant: 101% Serum: 102% Plasma: 87% |
| Assay time | 60 minutes |
| Species reactivity | Human |
Background
MCP-1, also known as CCL2, is a chemokine belonging to the C-C chemokine family. It plays a crucial role in various physiological processes such as inflammation, immune regulation, and cell migration. MCP-1/CCL2 primarily functions by binding to the C-C chemokine receptor CCR2, thereby guiding monocytes and other inflammatory cells to migrate to sites of inflammation, contributing to the inflammatory response and immune regulation. Overexpression of MCP-1/CCL2 is closely associated with the pathogenesis and progression of various diseases, including inflammatory diseases, autoimmune disorders, cancer, and metabolic disorders. As a result, MCP-1/CCL2 has emerged as a potential therapeutic target, and researchers are exploring therapeutic strategies targeting MCP-1/CCL2 in the hope of impacting the treatment of related diseases.
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