SKU: 96815615999

ABCC1 Recombinant Rabbit mAb (S-2254-35)

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Description

ABCC1 Recombinant Rabbit mAb (S-2254-35)Product Specification Host Rabbit Antigen ABCC1 Synonyms Multidrug resistance associated protein 1; ATP binding cassette sub family C member 1; Glutathione S conjugate translocating ATPase ABCC1; Leukotriene C (4) transporter (LTC4 transporter); MRP; MRP1 Immunogen Synthetic Peptide Location Cell membrane Accession P33527 Clone Number S 2254 35 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Positive Sample PANC 1, A549

Product Specification


Host Rabbit
Antigen ABCC1
Synonyms Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C (4) transporter (LTC4 transporter); MRP; MRP1
Immunogen Synthetic Peptide
Location Cell membrane
Accession P33527
Clone Number S-2254-35
Antibody Type Recombinant mAb
Isotype IgG
Application WB
Reactivity Hu
Positive Sample PANC-1, A549
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000-1:2000 Hu

Background

ABCC1, also known as multidrug resistance-associated protein 1 (MRP1), is a 180–190 kDa integral membrane protein that belongs to the ATP-binding cassette (ABC) transporter superfamily. It contains two membrane-spanning domains, each with six α-helices, and two nucleotide binding domains, along with an additional third membrane-spanning domain. This protein functions as a multispecific organic anion transporter, with substrates including oxidized glutathione, cysteinyl leukotrienes, activated aflatoxin B1, glucuronides, and sulfate conjugates of steroid hormones and bile salts. It is highly conserved and expressed in various tissues, particularly in the lungs, spleen, testes, kidneys, placenta, thyroid, bladder, adrenal glands, and endothelium cells of the blood-brain barrier. ABCC1 plays a significant role in multidrug resistance of cancerous tumor cells by transporting chemotherapeutic drugs out of the cells. Additionally, it has been a point of interest in Alzheimer's disease research due to its ability to decrease β-amyloid accumulation in the brain.

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Exchange/Return Notes
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SKU: 96815615999

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4.3 ★★★★★
Based on 11 reviews
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Pritesh Patel
Omaha, US
★★★★★ 3
Good product
Good product
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 2, 2026
S
Verified Purchase
stanley h.
West Palm Beach, US
★★★★★ 5
Nice Suit For The Price
This suit was a time-saver! My wife ordered a tux that wasn't going to make it for a formal occasion, so this was ordered and came within three days. It was a good thing she purchased 2, in case of sizing errors. The extra large pants worked, but sizing down to the large jacket & vest made the best combination/fit. We didn't go with the blue/black bow tie & flower it came with, but may for another event. However, being able to work interchangeably at a low price was rewarding!! Thought to add comments that the look of this suit is pleasing (though it's not the best thread). The workmanship gives it a 5 and even greater. The compliments were many. I do suggest using a good steam iron that will eliminate the wrinkles, without creating unwanted creases, while barely touching the suit; but, definitely follow the creases in the pants leg.
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Reviewed in the United States on March 20, 2025
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Verified Purchase
Peggy Cole
Cuba, US
★★★★★ 5
Disappointed
Size: XX-Large, Color: Light Grey, Size: XX-Large, Color: Light Grey
Overview of the Purchase Experience I recently ordered a 3-piece suit for my significant other, who is quite tall at 6’8”. I was excited about this purchase, hoping it would be a stylish addition to his wardrobe. However, upon receiving the suit, I encountered several issues that I feel compelled to share. Color Discrepancy One of the most disappointing aspects of this order was the color inconsistency. The suit was supposed to be a cohesive set, but it arrived with two different colors. This mismatch not only detracted from the overall aesthetic but also made it difficult to wear as a complete outfit. When purchasing a suit, especially a three-piece one that includes trousers, a vest, and a jacket, one expects all pieces to match in color and style. Unfortunately, this was not the case here. Quality Concerns In addition to the color issues, I found the quality of the fabric and construction to be subpar. The material felt cheap and did not have the durability or elegance one would expect from a suit. The stitching appeared uneven in places, and there were loose threads that raised concerns about its longevity. A well-made suit should exude quality and craftsmanship; however, this product fell short on both counts. Fit Issues Related to Height Given my significant other’s height (6’8”), finding suits that fit well can be challenging. While I cannot recall his exact weight at this moment, it’s important to note that tall individuals often require tailored fits or specific sizing options that accommodate their stature. Unfortunately, even if the colors had matched and the quality had been better, I doubt this suit would have fit him properly without additional alterations. Conclusion Overall, my experience with this 3-piece suit has been disappointing due to color discrepancies and poor quality construction. For anyone considering purchasing this item for someone tall or for themselves, I would recommend looking elsewhere unless you are prepared for potential issues with fit and appearance. Peggy Cole FabFashiion not approved
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Reviewed in the United States on September 24, 2024
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Verified Purchase
Jennifer Lee
Alexandria, US
★★★★★ 5
Excellent Affordable Suit for Special Occasions
Size: Large, Color: Black, Size: Large, Color: Black
Bought this for prom and was very happy with how it looked. The jacket is a nice medium weight and looked great on. We ordered a large, which was slightly big, but after having the suit tailored it fit perfectly. My son received many compliments and looked amazing.
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Reviewed in the United States on May 16, 2026
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Verified Purchase
Scache444
New York, US
★★★★★ 4
Worked out perfect. Great value, quality suit
Size: Small, Color: Black, Size: Small, Color: Black
Worked out perfectly for my son’s 8th grade formal. Pictured he is wearing a men’s small. Quality but a little baggy. It fit fine but we had the jacket altered to fit tighter around his back and the pants were hemmed and tapered. Great value for the money. Does not include a white shirt. Includes jacket, vest, pants, bow tie and pocket pin. 4 stars only because of baggy but some may like that fit.
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Reviewed in the United States on May 4, 2025

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