Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 20 - Sep 25
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Human folate receptor alpha Recombinant Rabbit mAb, PBS Only (SDT-719-684)Product Specification Host Rabbit Antigen Human folate receptor alpha Synonyms Folate receptor alpha; FR alpha; Adult folate binding protein (FBP); Folate receptor 1; Folate receptor; adult; KB cells FBP; Ovarian tumor associated antigen MOv18; FOLR; FOLR1 Immunogen Synthetic Peptide Location Secreted, Endosome, Cell membrane Accession P15328 Clone Number SDT 719 684 Antibody Type Recombinant mAb Isotype IgG Application IHC P Reactivity Hu
Product Specification
| Host | Rabbit |
| Antigen | Human folate receptor alpha |
| Synonyms | Folate receptor alpha; FR-alpha; Adult folate-binding protein (FBP); Folate receptor 1; Folate receptor; adult; KB cells FBP; Ovarian tumor-associated antigen MOv18; FOLR; FOLR1 |
| Immunogen | Synthetic Peptide |
| Location | Secreted, Endosome, Cell membrane |
| Accession | P15328 |
| Clone Number | SDT-719-684 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IHC-P |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:100-1:250 | Hu |
Background
Human folate receptor alpha (FOLR1) is a glycoprotein that plays a crucial role in the transport of folate, an essential vitamin, into cells. This receptor is highly expressed in certain tissues and is particularly notable for its involvement in various physiological processes including embryonic development and cellular proliferation. Its overexpression has been observed in numerous cancers, such as ovarian, lung, and breast cancer, making it a potential target for cancer diagnosis and targeted therapy. By binding to folate or folate analogs, FOLR1 facilitates the internalization of these molecules via endocytosis, thereby providing cells with the necessary folate for metabolic functions like DNA synthesis and repair.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy