SKU: 89088882300

APC Mouse Anti-Human CD197 Antibody (S-R704)

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Description

APC Mouse Anti-Human CD197 Antibody (S-R704)Product Specification Host Mouse Antigen CD197 Synonyms C C chemokine receptor type 7; C C CKR 7; CC CKR 7; CCR 7; BLR2; CDw197; Epstein Barr virus induced G protein coupled receptor 1 (EBI1; EBV induced G protein coupled receptor 1); MIP 3 beta receptor; CCR7; CMKBR7; EBI1; EVI1 Location Cell membrane Accession P32248 Clone Number S R704 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification

Product Specification


Host Mouse
Antigen CD197
Synonyms C-C chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR-7; BLR2; CDw197; Epstein-Barr virus-induced G-protein coupled receptor 1 (EBI1; EBV-induced G-protein coupled receptor 1); MIP-3 beta receptor; CCR7; CMKBR7; EBI1; EVI1
Location Cell membrane
Accession P32248
Clone Number S-R704
Antibody Type Mouse mAb
Isotype IgG2a,k
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Purification Protein A
Concentration 0.2 mg/ml
Conjugation APC
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 30

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD197, also known as CCR7 (C-C chemokine receptor type 7), is an important G protein-coupled receptor primarily expressed on mature dendritic cells, naïve T cells, and certain B cell subsets. It mediates the directed migration and homing of immune cells by specifically recognizing and binding its ligands, CCL19 and CCL21. This interaction plays a central role in recruiting lymphocytes to secondary lymphoid organs, such as lymph nodes and the spleen, which is essential for immune surveillance, the initiation of adaptive immune responses, and the maintenance of immune homeostasis. Furthermore, aberrant expression of CCR7 is observed in various cancers and is closely associated with tumor lymph node metastasis and poor prognosis, making it a potential therapeutic target for cancer treatment and immune modulation. Its signaling pathway involves multiple downstream effector molecules, including the PI3K/Akt and MAPK pathways, which finely regulate cell survival, proliferation, and migratory behavior.

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SKU: 89088882300

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Alan M
Carnegie, US
★★★★★ 5
Comfortable, Hypoallergenic, and Great Value
Size: King (Pack of 2), Style: Soft, Configuration: Pillow
These pillows are a solid upgrade for everyday sleep. They’re soft but still provide enough support for both back and stomach sleeping, and the down-alternative fill is perfect if you’re sensitive to allergens. The microfiber cover feels smooth and well-made, and they fluff up nicely after decompressing. Overall, a comfortable and affordable set that gets the job done.
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Reviewed in the United States on March 22, 2026
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Amazon Customer
Birmingham, US
★★★★★ 5
Definitely worth buying
Size: King (Pack of 2), Style: Soft, Configuration: Pillow
These pillows are AWESOME! Soft, comfortable and fill up the pillowcases well.
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Reviewed in the United States on May 21, 2026
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Jusvette Sierra
Los Angeles, US
★★★★★ 5
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Size: King (Pack of 2), Style: Soft, Configuration: Pillow
These pillows I’ve use for a while now are so fluffy and soft and comfortable and perfect for stomach and back sleepers They give gentle support and are easy to wash Great quality and also water resistance for the price
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Reviewed in the United States on April 2, 2026
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Barb
Phoenix, US
★★★★★ 4
Best for decorating. Not sleeping.
Size: King (Pack of 2), Style: Soft, Configuration: Pillow
These are perfect as inserts for decorative shams and the price was great. I don't think that I would ever want to use them for sleeping. They seem slightly lumpy and don't look they would last for very long with constant use.
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Reviewed in the United States on January 16, 2026
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Andy
Massapequa, US
★★★★★ 5
Great value, soft but still supportive – perfect for everyday use
Size: King (Pack of 2), Style: Soft, Configuration: Pillow
Really impressed with these pillows for the price. They’re soft but still provide decent support, and work well for both back and side sleeping. No weird smell and very comfortable overall. Definitely a great budget option! 👍
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Reviewed in the United States on March 31, 2026

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