SKU: 3548355507

Biotin Rabbit Anti-Human CD326 Antibody (S-1009-76)

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Description

Biotin Rabbit Anti-Human CD326 Antibody (S-1009-76)Product Specification Host Rabbit Antigen CD326 Synonyms Epithelial cell adhesion molecule; Ep CAM; Adenocarcinoma associated antigen; Cell surface glycoprotein Trop 1; Epithelial cell surface antigen; Epithelial glycoprotein (EGP); Epithelial glycoprotein 314 (EGP314; hEGP314); KS 1 4 antigen; KSA; Major gastrointestinal tumor associated protein GA733 2; Tumor associated calcium signal transducer 1; GA733 2; M1S2; M4S1; MIC18; TACSTD1; TROP1

Product Specification


Host Rabbit
Antigen CD326
Synonyms Epithelial cell adhesion molecule; Ep-CAM; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; Epithelial cell surface antigen; Epithelial glycoprotein (EGP); Epithelial glycoprotein 314 (EGP314; hEGP314); KS 1/4 antigen; KSA; Major gastrointestinal tumor-associated protein GA733-2; Tumor-associated calcium signal transducer 1; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
Immunogen Recombinant Protein
Location Cell membrane, Cell junction
Accession P16422
Clone Number S-1009-76
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Hu
Positive Sample HT-29
Purification Protein A
Concentration 0.2 mg/ml
Conjugation Biotin
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1.25μl per million cells in 100μl volume Hu

Background

Epithelial cell adhesion molecule (EpCAM), also known as CD326 among other names, is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell–cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.

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SKU: 3548355507

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4.4 ★★★★★
Based on 15 reviews
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Morgan S
Birmingham, US
★★★★★ 5
Perfect for learning about bugs!
Format: Board book
Purchased this because my kids class is learning about bugs. It is so cute, and both my kids my 3 year old and almost 2 year old love it! The pictures are so cute, and they really do go through each bug, making it educational. Such a fun book at a great price for 1-3 year olds.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 19, 2024
S
Verified Purchase
Soft-Hearted Scribbler
Waukegan, US
★★★★★ 5
Humor and Heart
Format: Kindle
Soccer superstar Sage needs a serious girlfriend to boost her image. Willa needs a plus one for her ex’s bachelorette party. When the two former high school classmates reconnect, they devise a plan to enter a fake relationship, but how long can it stay pretend? Never Mine has a fun and heartwarming fake romance plot, likable characters, and many laugh out loud scenes. Willa and Sage’s relationship is destined to be something special from the moment they reconnect at their high school reunion, but watching them finally figure that out for themselves is entertaining and delightful. Fans of great sapphic fauxmance with plenty of humor and heart will love Never Mine.
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Reviewed in the United States on October 7, 2024
C
Verified Purchase
Carpediem
Chelsea, US
★★★★★ 4
Gay but not out
Format: Kindle
At a time when five women of the US national soccer team are out, Sage Bryson is struggling. A star player, but out of the squad with injury, she stumbles into a secret attraction to a dorky zoo events co-ordinator. Willa. The feeling is mutual but lacks Sage's long term commitment. A series of some unusual, but amusing, situations draws them together. But commitment fears on both sides keeps them apart. Clever writing with some amusing one-liners, the story bumps along the 'will she, won't she' road, with occasional cliff hangers. A good read.
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Reviewed in the United States on August 21, 2024
K
Verified Purchase
Kathy
Waukegan, US
★★★★★ 5
Great chemistry and inspirational!
Format: Kindle
Injured World Cup and Olympic soccer star Sage Carson meets up with sweet Willa Bellamy, an events coordinator for the Denver Zoo, at their fifteen high school reunion. Both seemingly out of their elements they ditch it to go out for pizza at the favorite high school joint and develop a mutually satisfying plan as fake girlfriends. Sage needs to be seen with Willa to help improve her messy rebellious persona while Willa needs a date to her ex's wedding and bachelorette weekend. Not only was this story beautifully crafted with Bryce's wonderful dialogue, sense of humor and flirty interactions, but the development of the characters, including secondary, grew throughout the book. I loved the impact Willa had on Sage just by being her authentic self and I loved the belief Willa had in Sage to think beyond her career as a soccer star. They were good for each other, truly seeing each other's finest capabilities. I enjoyed the settings of the beach, soccer world and zoo, but it was their beautiful journey together that made this book so good. I highly recommend it!
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Reviewed in the United States on June 9, 2021
P
Verified Purchase
Ps58
Bozeman, US
★★★★★ 5
What a delightful fake romance story.
Format: Kindle
Will a is nice to the point of everyone taking advantage of her. Sage is so wrapped up in herself she can't see how lost she has become. These two make a much needed contract to fake a relationship for personal connection. The characters are are funny, have an instant attraction and spend months trying to avoid feelings. Bryce Oakley gives a great no fake angst story about mutual attraction that brings friendship and an inner strength to the MC. It is so fun to read with moments that will touch your heart. I am never disappointed with this authors writing.
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Reviewed in the United States on November 2, 2021

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