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Description
ALDH1L1 Recombinant Rabbit mAb (S-2885-49)Product Specification Host Rabbit Antigen ALDH1L1 Synonyms Cytosolic 10 formyltetrahydrofolate dehydrogenase; 10 FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1Imported; FTHFD Immunogen Synthetic Peptide Location Cytoplasm Accession O75891 Clone Number S 2885 49 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IF Reactivity Hu, Ms, Rt Positive Sample mouse liver, mouse kidney, rat liver, rat kidney Predicted Reactivity Or
Product Specification
| Host | Rabbit |
| Antigen | ALDH1L1 |
| Synonyms | Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1Imported; FTHFD |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | O75891 |
| Clone Number | S-2885-49 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IF |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | mouse liver, mouse kidney, rat liver, rat kidney |
| Predicted Reactivity | Or |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:5000 | Ms, Rt |
| IHC-P | 1:2000 | Hu, Ms, Rt |
| IF | 1:500 | Ms, Rt |
Background
ALDH1L1 (10-formyltetrahydrofolate dehydrogenase) is a 902-residue cytosolic enzyme that oxidizes 10-formyl-THF to CO₂ and THF while reducing NADP⁺ to NADPH, thereby governing one-carbon flux for purine synthesis, mitochondrial 10-formyl-THF export, and cellular redox balance, and its selective expression in astrocytes makes it the most widely used immunohistochemical marker of these glial cells across the mammalian CNS.
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