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Description
FGL2 His Tag Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms FGL2, T49, pT49 Accession A0A2K5WID3 Amino Acid Sequence Pro204 Pro439, with C terminal 8*His PVQHLIYKDCSDYYAIGKRSSETYRVTPDPKNRSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQDYKAGFGNLRREFWLGNDKIHLLTKSKEMILRIDLEDFNGVKLYALYDQFYVANEFLKYRLHVGNYNGTAGDALRFNKHYNHDLKFFTTPDKDNDRYPSGNCGLYYSSGWWFDACLSANLNGKYYHQKYRGVRNGIFWGTWPGVSEAHPGGYKSSFKEAKMMIRPKHFKPGGGSHHHHHHHH Expression System HEK293 Molecular Weight 36 42kDa Purity >95%
Product Specification
| Species | Cynomolgus |
| Synonyms | FGL2, T49, pT49 |
| Accession | A0A2K5WID3 |
| Amino Acid Sequence | Pro204-Pro439, with C-terminal 8*His PVQHLIYKDCSDYYAIGKRSSETYRVTPDPKNRSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQDYKAGFGNLRREFWLGNDKIHLLTKSKEMILRIDLEDFNGVKLYALYDQFYVANEFLKYRLHVGNYNGTAGDALRFNKHYNHDLKFFTTPDKDNDRYPSGNCGLYYSSGWWFDACLSANLNGKYYHQKYRGVRNGIFWGTWPGVSEAHPGGYKSSFKEAKMMIRPKHFKPGGGSHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 36-42kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Feng Y. et al. (2020) Fibrinogen-Like Protein 2 (FGL2) is a Novel Biomarker for Clinical Prediction of Human Breast Cancer. Med Sci Monit. 26: e923531. 2、Hou X. et al. (2021) Regulatory T cells induce polarization of pro-repair macrophages by secreting sFGL2 into the endometriotic milieu. Commun Biol. 4(1): 499. |
Background
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. Fibrinogen-like protein 2 (FGL2) exists in both soluble and membrane forms. Soluble fibrinogen-like protein 2 (sFGL2) has been recently identified as a novel effector molecule of Tregs and plays a pivotal role in regulating both innate and adaptive immunity. FGL2 mediates its immunosuppressive activity by binding to inhibitory FcγRIIB (CD32B) receptors expressed by antigen presenting cells (APC), including dendritic cells (DC) and B cells, and thus sFGL2 may inhibit the maturation of DC, resulting in the suppression of effector T cell responses and inducing apoptosis of B cells.
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4.6 ★★★★★
Based on 29 reviews
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Product Reviews
★★★★★ 5
Perfect suit for boys
Color: Navy Blue, Size: 12 Years, Color: Navy Blue, Size: 12 Years
So thankful for this! This suit was perfect! My son wore this all night playing and the durability of this fabric is on another level. Wasn't too thick, looked really nice, and fabric was really soft. It also blended really well with the suits from Mens Warehouse.
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Reviewed in the United States on June 2, 2026
★★★★★ 5
Perfect!
Color: Royal Blue, Size: 12 Years, Color: Royal Blue, Size: 12 Years
I was nervous about purchasing something like this at the last minute. But based on the previous reviews I decided to take a chance.
The suit is nice and the material feels really good. Not thin or cheap at all. My son looked so handsome and grown up. He’s on the slim side so he does have extra room but I don’t mind it because he can definitely grow into it. I did purchase a separate tie because I wanted a pattern to complement the blue.
I’d definitely purchase again!
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Reviewed in the United States on April 15, 2026
★★★★★ 4
Big in waist
Color: Grey, Size: 12 Years
Very nice suit, the material was nice. My son is an average build, the suit fit on the length but unfortunately the pants were huge in the waist. Even with the inside waist adjuster and a belt he couldn't wear them. Which was disappointing because overall the rest of the suit was perfect!
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Reviewed in the United States on May 31, 2026
★★★★★ 5
Perfect
Color: Royal Blue, Size: 8 Years
The tops fit perfectly however my 6 year old is very tall and slim so the pants were a little big but at least the adjustable straps on the inside will help..love the color
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Reviewed in the United States on May 5, 2026
★★★★★ 5
Worth the money
Color: Navy Blue, Size: 12 Years, Color: Navy Blue, Size: 12 Years
Came just in time for my son graduation and he was very sharp and handsome
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Reviewed in the United States on May 31, 2026