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Description
COL3A1(PIIINP) Recombinant Rabbit mAb (SDT-149-50)Product Specification Host Rabbit Antigen COL3A1(PIIINP) Synonyms Collagen alpha 1(III) chain Immunogen Recombinant Protein Location Secreted, Extracellular space, Extracellular matrix Accession P02461 Clone Number SDT 149 50 Antibody Type Rabbit mAb Application IHC P, IF Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months
Product Specification
| Host | Rabbit |
| Antigen | COL3A1(PIIINP) |
| Synonyms | Collagen alpha-1(III) chain |
| Immunogen | Recombinant Protein |
| Location | Secreted, Extracellular space, Extracellular matrix |
| Accession | P02461 |
| Clone Number | SDT-149-50 |
| Antibody Type | Rabbit mAb |
| Application | IHC-P, IF |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:500 | null |
| IF | 1:100 | null |
Background
PIIINP, also known as the collagen alpha-1(III) chain, is a protein that in humans is encoded by the COL3A1 gene. Three alpha 1 chains are required to form the type III collagen molecule which has a long triple-helical domain. Type III collagen, an extracellular matrix protein, is synthesized by cells as a pre-procollagen. It is found as a major structural component in hollow organs such as large blood vessels, uterus and bowel. Other functions of type III collagen include interaction with platelets in the blood clotting cascade and it is also an important signalling molecule in would healing. Mutations in the COL3A1 gene cause the vascular type of Ehlers-Danlos syndrome.
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