Pay in installments of $30.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 25 - Aug 30
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Invivo anti-Rat TCR γ/δ Recombinant mAbProduct Specification Host Mouse Antigen TCR Location Cell membrane Accession A0A8I6G2Y5 Clone Number S 3864 Antibody Type Mouse mAb Application FCM, in vivo T cell depletion Reactivity Rt Purification Protein G Concentration 5 mg ml Purity >95% (Determined by SDS PAGE) Endotoxin <1EU mg Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4, containing no preservative Stability & Storage 2 to 8 C for 2 weeks under sterile
Product Specification
| Host | Mouse |
| Antigen | TCR γ/δ |
| Location | Cell membrane |
| Accession | A0A8I6G2Y5 |
| Clone Number | S-3864 |
| Antibody Type | Mouse mAb |
| Application | FCM, in vivo γ/δ T cell depletion |
| Reactivity | Rt |
| Purification | Protein G |
| Concentration | 5 mg/ml |
| Purity | >95% (Determined by SDS-PAGE) |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage | 2 to 8 °C for 2 weeks under sterile conditions; |
Background
TCR γ/δ protein is a heterodimeric receptor—composed of one γ and one δ chain, each with a variable (V) and constant (C) immunoglobulin-like domain plus a short cytoplasmic tail—whose extracellular V regions recognize phosphoantigens, stress molecules or butyrophilin family ligands without MHC restriction, while its membrane-proximal C regions associate with CD3δε, γε and ζζ signaling modules; upon ligand binding the γ/δ chains undergo conformational change that exposes CD3 ITAMs to Lck-mediated phosphorylation, recruiting ZAP-70 and triggering a Vav1–PLC-γ1 cascade that elevates intracellular Ca²⁺, activates PKC-θ, NFAT, NF-κB and AP-1, and thereby drives γδ T-cell cytotoxicity, cytokine release and tumor lysis.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy