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Description
FbpB/Ag85B Recombinant Rabbit mAb (S-3325-22)Product Specification Host Rabbit Antigen FbpB Ag85B Synonyms Diacylglycerol acyltransferase mycolyltransferase Ag85B; DGAT; 30 kDa extracellular protein; Acyl CoA: diacylglycerol acyltransferase; Antigen 85 complex B (85B; Ag85B); Extracellular alpha antigen; Fibronectin binding protein B (Fbps B); fbpB Immunogen Recombinant Protein Location Secreted Accession P9WQP0 Clone Number S 3325 22 Antibody Type Recombinant mAb Isotype IgG Application WB
Product Specification
| Host | Rabbit |
| Antigen | FbpB/Ag85B |
| Synonyms | Diacylglycerol acyltransferase/mycolyltransferase Ag85B; DGAT; 30 kDa extracellular protein; Acyl-CoA:diacylglycerol acyltransferase; Antigen 85 complex B (85B; Ag85B); Extracellular alpha-antigen; Fibronectin-binding protein B (Fbps B); fbpB |
| Immunogen | Recombinant Protein |
| Location | Secreted |
| Accession | P9WQP0 |
| Clone Number | S-3325-22 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Mycobacterium tuberculosis |
Background
FbpB/Ag85B is a 30 kDa secreted fibronectin-binding mycolyltransferase that catalyzes the transfer of mycolic acids to arabinogalactan and trehalose monomycolates, thereby building trehalose dimycolate (cord factor) and maintaining the integrity of the mycobacterial cell wall, while simultaneously functioning as the immunodominant antigen of the antigen 85 complex that strongly induces Th1-biased cellular and humoral immunity through IFN-γ, IL-2 and antibody production, making it a key adhesin for host-cell attachment and a leading subunit vaccine candidate against tuberculosis.
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