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Description
S-RMab® CD14 Recombinant Rabbit mAb(SDT-060-50)Product Specification Host Rabbit Antigen CD14 Synonyms Myeloid cell specific leucine rich glycoprotein Immunogen Synthetic Peptide Location Membrane Accession P08571 Clone Number SDT 060 50 Antibody Type Rabbit mAb Application WB, IHC P, ICC, FC, IP Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt
Product Specification
| Host | Rabbit |
| Antigen | CD14 |
| Synonyms | Myeloid cell-specific leucine-rich glycoprotein |
| Immunogen | Synthetic Peptide |
| Location | Membrane |
| Accession | P08571 |
| Clone Number | SDT-060-50 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, ICC, FC, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:2000 | |
| WB | 1:1000 | |
| IP | 1:25 | |
| FACS | 1:500 | |
| ICC | 1:500 |
Background
CD14 (cluster of differentiation 14) is a human protein made mostly by macrophages as part of the innate immune system. It helps to detect bacteria in the body by binding lipopolysaccharide (LPS), a pathogen-associated molecular pattern (PAMP). CD14 exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol (GPI) tail (mCD14), the other a soluble form (sCD14). Soluble CD14 either appears after shedding of mCD14 (48 kDa) or is directly secreted from intracellular vesicles (56 kDa).
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Exchange/Return Notes
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