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Description
CLDN7 Recombinant Rabbit mAb (SDT-077-17)Product Specification Host Rabbit Antigen CLDN7 Synonyms CEPTRL2, CPETRL2, Claudin 7, Claudin 7 Immunogen Synthetic Peptide Location Intracellular Accession O95471 Clone Number SDT 077 17 Antibody Type Rabbit mAb Application IHC P Reactivity Hu, Ms Purification Protein A Concentration 0. 5mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of
Product Specification
| Host | Rabbit |
| Antigen | CLDN7 |
| Synonyms | CEPTRL2, CPETRL2, Claudin-7, Claudin 7 |
| Immunogen | Synthetic Peptide |
| Location | Intracellular |
| Accession | O95471 |
| Clone Number | SDT-077-17 |
| Antibody Type | Rabbit mAb |
| Application | IHC-P |
| Reactivity | Hu, Ms |
| Purification | Protein A |
| Concentration | 0.5mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:2000 |
Background
Claudin is a transmembrane protein with four transmembrane domains. Claudin-7 (Cldn7) is a member of the claudin family, and its basic function is to maintain cell polarity and form tight junctions. CLDN7 has a full-length form (211 amino acids) and a C-terminal truncated form (158 amino acids). Recent studies have shown that low expression of the Cldn7 protein is found in a variety of malignant tumors, such as lung cancer, breast cancer, pancreatic cancer, and colorectal cancer (CRC).
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