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Description
Tissue factor Recombinant Rabbit mAb (S-893-34)Product Specification Host Rabbit Synonyms TF, Coagulation factor III, Thromboplastin, CD142, F3 Immunogen Recombinant Protein Location Membrane Accession P13726 Clone Number S 893 34 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, FCM Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12
Product Specification
| Host | Rabbit |
| Synonyms | TF, Coagulation factor III, Thromboplastin, CD142, F3 |
| Immunogen | Recombinant Protein |
| Location | Membrane |
| Accession | P13726 |
| Clone Number | S-893-34 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, FCM |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| IHC-P | 1:200 | null |
| FCM | 1:50 | null |
Background
Tissue factor, also called platelet tissue factor, factor III, or CD142, is a protein encoded by the F3 gene, present in subendothelial tissue and leukocytes. Its role in the clotting process is the initiation of thrombin formation from the zymogen prothrombin. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces.
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