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Description
SQSTM1/p62 Recombinant Rabbit mAb (S-778-1)Product Specification Host Rabbit Synonyms Sequestosome 1, EBI3 associated protein of 60 kDa (EBIAP, p60), Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin binding protein p62, ORCA, OSIL Immunogen Synthetic Peptide Location Cytoplasm Accession Q13501 Clone Number S 778 1 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, ICFCM, IP Reactivity Hu, Ms, Rt Predicted Reactivity Or Purification Protein A
Product Specification
| Host | Rabbit |
| Synonyms | Sequestosome-1, EBI3-associated protein of 60 kDa (EBIAP, p60), Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin-binding protein p62, ORCA, OSIL |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | Q13501 |
| Clone Number | S-778-1 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, ICFCM, IP |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Or |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied. |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IP | 1:50 | |
| IHC-P | 1:500 | |
| ICC | 1:500 | |
| ICFCM | 1:500 |
Background
Sequestosome-1 is a protein that in humans is encoded by the SQSTM1 gene. Also known as the ubiquitin-binding protein p62, it is an autophagosome cargo protein that targets other proteins that bind to it for selective autophagy. By interacting with GATA4 and targeting it for degradation, it can inhibit GATA-4 associated senescence and senescence-associated secretory phenotype. Mutations in SQSTM1 are a common cause of Paget's disease of bone.
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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4.8 ★★★★★
Based on 17 reviews
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Product Reviews
★★★★★ 4
Durable
Color: E) 8-Pack 2.5" Balls (Yellow)
My dogs love them. They are very bouncy, and ideal size, and durable. Great alternative to a tennis ball which in my house only last 30 minutes.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 23, 2026
★★★★★ 5
Toughest dang balls I ever played with
Color: D) 4-Pack 3" Balls (Yellow), Color: D) 4-Pack 3" Balls (Yellow)
These things are amazing. We have a ball obsessed Husky mix and he has destroyed Kongs, Chuck Its, and a whole lot of other ball shaped objects. These things? We bought the 4 pack because we bought 4 Chuck Its and they lasted a year, all 4 of them only a year, before they were destroyed. A year after buying these? We only bought more because he lost 3 of them. I think we did find one under the dresser after buying this pack... But the others? They either ended up thrown over the fence into the woods or lost in the holes in the yard the monster digs up. Other than a few pockmarks from his teeth and maybe some mud, they may as well be brand new even after a year or two. Probably the most chew resistant thing we've ever bought him. They're really solid rubber and since he hasn't managed to bite into them to take out a chunk, they're safe as hell. Being as big as they are, I don't worry he's gonna choke unattended on them like the usual size of ball. About the only concern is forcing breaks so he can have breathing moments when he manages to talk us into fetch outside. It fits in the larger Chuck It thrower too, so we haven't lost any value from having those torn up.
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Reviewed in the United States on April 26, 2026
★★★★★ 5
Sturdy bouncy fun!
Color: D) 4-Pack 3" Balls (Yellow), Color: D) 4-Pack 3" Balls (Yellow)
Great product. My big 70lb Sheppard puppy loves it, hasn’t stopped playing with it since it arrived. She throws it about and chases it, had a good chew on it and even put it in her favorite toys bin. Sturdy, firm and very bouncy. And there are 3 more in the bag for an awesome price. Bright color will make it easy to find and holes thru it will prevent choking and I can string it on a line for training play.
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Reviewed in the United States on November 28, 2025
★★★★★ 5
Dogs love these
Color: C) 2-Pack 2.5" Balls (Yellow)
Great quality balls for tough chewers. I love them, but wish the orange ones were available more...I've been checking cuz they are easier to find in the yard than the green that blends in. Our dogs love them and I like the weight for throwing.
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Reviewed in the United States on May 9, 2026
★★★★★ 5
The perfect toy for dogs!
Style: The Duo
This is perfect when you have 2 dogs who love to play Fetch! They no longer have to chase after the same ball! The balls that come with it are very sturdy, and the launcher sends both balls far enough away so that both dogs get plenty of exercise. It’s definitely worth the price!
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Reviewed in the United States on May 26, 2026
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