SKU: 66607007687

CD36/SR-B3 His Tag Protein, Mouse

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Description

CD36/SR-B3 His Tag Protein, MouseProduct Specification Species Mouse Synonyms CD36, SR B3, SCARB3, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV Accession Q08857 Amino Acid Sequence Gly30 Lys439, with C terminal 10*His

Product Specification


Species Mouse
Synonyms CD36, SR-B3, SCARB3, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV
Accession Q08857
Amino Acid Sequence Gly30-Lys439, with C-terminal 10*His GDMLIEKTIKREVVLEEGTTAFKNWVKTGTTVYRQFWIFDVQNPDDVAKNSSKIKVKQRGPYTYRVRYLAKENITQDPEDHTVSFVQPNGAIFEPSLSVGTEDDNFTVLNLAVAAAPHIYQNSFVQVVLNSLIKKSKSSMFQTRSLKELLWGYKDPFLSLVPYPISTTVGVFYPYNDTVDGVYKVFNGKDNISKVAIIESYKGKRNLSYWPSYCDMINGTDAASFPPFVEKSRTLRFFSSDICRSIYAVFGSEIDLKGIPVYRFVLPANAFASPLQNPDNHCFCTEKVISNNCTSYGVLDIGKCKEGKPVYISLPHFLHASPDVSEPIEGLHPNEDEHRTYLDVEPITGFTLQFAKRLQVNILVKPARKIEALKNLKRPYIVPILWLNETGTIGDEKAEMFKTQVTGKIKGGGSGGGSHHHHHHHHHH
Expression System HEK293
Molecular Weight 77-88kDa
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Okamoto F. et al. (1998) CD36 abnormality and impaired myocardial long-chain fatty acid uptake in patients with hypertrophic cardiomyopathy. Jpn Circ J. 62: 499-504.

2、Tanaka T. et al. (1997) Is CD36 deficiency an etiology of hereditary hypertrophic cardiomyopathy? J Mol Cell Cardiol. 29: 121-127.

3、Forte E. et al. (2018) The interstitium in cardiac repair: role of the immune-stromal cell interplay. Nat Rev Cardiol. 15: 601-616.

4、Coraci I S. et al. (2002) CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer’s disease brains and can mediate production of reactive oxygen species in response to -amyloid fibrils. Am. J. Pathol. 160: 101-112.

Background

CD36 belongs to the scavenger receptor class B (SR-B), a family of highly glycosylated transmembrane receptors with a wide range of ligand recognition sites. It has been reported that glycosylation of CD36 is required for trafficking of intracellular CD36 to the cell surface membrane. Because of its wide range of ligands, CD36 has plenty of functions, including but not limited to recognizing and ingesting lipids, participating in the process of inflammatory response, signal transduction, and apoptosis. The expression occurs in monocytes/macrophages and microglia as well as various other cells and tissues, including microvascular endothelial cells, platelets, adipocytes, and the heart. CD36 promotes the podocyte injury in many kidney diseases including primary nephrotic syndrome, obesity-related glomerulopathy, and diabetic nephropathy. Moreover, genetic knockout or antagonist blockade of CD36 could alleviate kidney injury indicating that CD36 is a potential therapeutic target.
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SKU: 66607007687

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4.4 ★★★★★
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S. Meade
Belleville, US
★★★★★ 5
It works.
I was skeptical of this product because of how I intended to use it. Sometimes, especially in summer, moisture accumulates in the crease of my legs (where they attach to my body). And, as a result, I get severely chafed to the point of breaking skin and bleeding (or at least seeping serum). I figured this could just wash away in the moisture. But, it didn't. I did very meticulous cleaning and drying and then applied this ointment. At least twice daily. And in just a few days my skin was healing. I'd say less than a week and I was back to normal. Highly recommended.
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Reviewed in the United States on February 3, 2021
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Verified Purchase
K Seneca
Port Orchard, US
★★★★★ 4
Great skin relief, but not Vegan.
Great product but it's not Vegan. As a nutritioist and vegetarian, I'm aware that true Vegans do not eat/use anything containing animals or animal by-producs. This contains beeswax which makes it vegetarian but not Vegan. That is the only reason why I'm giving it 4 stars rather than 5. I bought this to use on 2 small patches of dry/scaly skin on my face. Everything else always says "itch relief" and contains strong chemicals which I prefer to not use, especially on my face. After just a couple weeks, the scaly skin is gone and the red is getting lighter every day. It smells very nice as well.
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Reviewed in the United States on May 7, 2021
G
Verified Purchase
Gerald Schoenburg
Dallas, US
★★★★★ 1
Not What I thought
This product came in a very small jar. The product looks exactly like Vaseline. This is supposed to help skin repair and itch. After a week it did Ineither!. I'm sorry but that's how I found this product, not what I wanted.
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Reviewed in the United States on August 23, 2024
L
Verified Purchase
Lady Diva Mystic
Dallas, US
★★★★★ 5
Wonderful 💋!!!!
Healed up my open wound quick, along with a burn I had. Just wish it was a much bigger container. This stuff is amazing!. I keep it always in my first aid kit. Love it!
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Reviewed in the United States on June 10, 2021
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Raymond Morgan
San Leandro, US
★★★★★ 3
Natrulo Skin Repair Cream
This is not "skin repair cream", this is a TINY jar of Vaseline petroleum jelly! I read back over the description page where I ordered it and it DOESN'T say that it ISN'T Vaseline, so it's my fault for expecting something different! Save your money and just buy a jar of Vaseline!!!!
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Reviewed in the United States on March 31, 2024

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