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Description
Biotinylated Fc γ RIV/CD16-2 His&Avi Tag Protein, MouseProduct Specification Species Mouse Synonyms Fc gamma RIV, CD16 2, Fcgr4 Accession A0A0B4J1G0 Amino Acid Sequence Gly21 Gln203, with C terminal 8*His&Avi tag GLQKAVVNLDPKWVRVLEEDSVTLRCQGTFSPEDNSIKWFHNESLIPHQDANYVIQSARVKDSGMYRCQTALSTISDPVQLEVHMGWLLLQTTKWLFQEGDPIHLRCHSWQNRPVRKVTYLQNGKGKKYFHENSELLIPKATHNDSGSYFCRGLIGHNNKSSASFRISLGDPGSPSMFPPWHQ GGGSGGGSHHHHHHHHGLNDIFEAQKIEWHE Expression System HEK293 Molecular Weight 28 35kDa Purity >95% by SDS PAGE
Product Specification
| Species | Mouse |
| Synonyms | Fc gamma RIV, CD16-2, Fcgr4 |
| Accession | A0A0B4J1G0 |
| Amino Acid Sequence | Gly21-Gln203, with C-terminal 8*His&Avi tag GLQKAVVNLDPKWVRVLEEDSVTLRCQGTFSPEDNSIKWFHNESLIPHQDANYVIQSARVKDSGMYRCQTALSTISDPVQLEVHMGWLLLQTTKWLFQEGDPIHLRCHSWQNRPVRKVTYLQNGKGKKYFHENSELLIPKATHNDSGSYFCRGLIGHNNKSSASFRISLGDPGSPSMFPPWHQ GGGSGGGSHHHHHHHHGLNDIFEAQKIEWHE |
| Expression System | HEK293 |
| Molecular Weight | 28-35kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Hirano M. et al. (2007) IgEb immune complexes activate macrophages through FcγRIV binding. Nature Immunology. 8: 762-771. |
Background
Fc γ RIV (Low affinity immunoglobulin gamma Fc region receptor IV), also known as CD16-2 (Fc γ RIV), belongs to the Fc γ receptor family. There are three types of Fc γ receptors: Fc γ RI (CD64), Fc γ RII (CD32) and Fc γ RIII (CD16). Fc γ RI (CD64) has a high affinity for IgG monomer, while Fc γ RII (CD32) and FC γ RIII (CD16) have a relatively low affinity for IgG. Human CD16 is encoded by two genes, Fc γ RIIIA and Fc γ RIIIB. The gene sequence of CD16-2 is more similar to that of human Fc γ RIIIA protein. The combination of FcγRIV and IgG2a can promote bone cell differentiation. The combination of FcγRIV and IgE can promotes macrophage-mediated phagocytosis, antigen presentation, and proinflammatory cytokine production.
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4.0 ★★★★★
Based on 9 reviews
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Product Reviews
★★★★★ 5
It works.
I was skeptical of this product because of how I intended to use it. Sometimes, especially in summer, moisture accumulates in the crease of my legs (where they attach to my body). And, as a result, I get severely chafed to the point of breaking skin and bleeding (or at least seeping serum). I figured this could just wash away in the moisture. But, it didn't. I did very meticulous cleaning and drying and then applied this ointment. At least twice daily. And in just a few days my skin was healing. I'd say less than a week and I was back to normal.
Highly recommended.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 3, 2021
★★★★★ 4
Great skin relief, but not Vegan.
Great product but it's not Vegan. As a nutritioist and vegetarian, I'm aware that true Vegans do not eat/use anything containing animals or animal by-producs. This contains beeswax which makes it vegetarian but not Vegan.
That is the only reason why I'm giving it 4 stars rather than 5.
I bought this to use on 2 small patches of dry/scaly skin on my face. Everything else always says "itch relief" and contains strong chemicals which I prefer to not use, especially on my face. After just a couple weeks, the scaly skin is gone and the red is getting lighter every day. It smells very nice as well.
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Reviewed in the United States on May 7, 2021
★★★★★ 1
Not What I thought
This product came in a very small jar.
The product looks exactly like Vaseline.
This is supposed to help skin repair and itch. After a week it did Ineither!.
I'm sorry but that's how I found this product, not what I wanted.
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Reviewed in the United States on August 23, 2024
★★★★★ 5
Wonderful 💋!!!!
Healed up my open wound quick, along with a burn I had. Just wish it was a much bigger container. This stuff is amazing!. I keep it always in my first aid kit. Love it!
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Reviewed in the United States on June 10, 2021
★★★★★ 3
Natrulo Skin Repair Cream
This is not "skin repair cream", this is a TINY jar of Vaseline petroleum jelly! I read back over the description page where I ordered it and it DOESN'T say that it ISN'T Vaseline, so it's my fault for expecting something different! Save your money and just buy a jar of Vaseline!!!!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 31, 2024
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