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Description
TrkC Fc Chimera Protein, HumanProduct Specification Species Human Synonyms TrkC, Ntrk3 Accession Q96CY4 Amino Acid Sequence Cys32 Asp428, with C terminal Human IgG1 Fc
Product Specification
| Species | Human |
| Synonyms | TrkC, Ntrk3 |
| Accession | Q96CY4 |
| Amino Acid Sequence | Cys32-Asp428, with C-terminal Human IgG1 Fc CPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Expression System | HEK293 |
| Molecular Weight | 95-115kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human Fc Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Khotskaya Y B. et al. (2017). Targeting TRK family proteins in cancer. Review. 173:58-66. |
Background
The tropomyosin receptor kinase (TRK) family includes TRKA, TRKB, and TRKC proteins, which are encoded by NTRK1, NTRK2 and NTRK3 genes, respectively. Binding of neurotrophins to TRK proteins induces receptor dimerization, phosphorylation, and activation of the downstream signaling cascades via PI3K, RAS/MAPK/ERK, and PLC-gamma. TrkC functions not only as an oncogene, but also act as a tumor suppressor via a manner of dependence receptor in human malignant tumors. TrkC is a potent oncoprotein expressed in tumors derived from multiple cell lineages, and functions as an active protein tyrosine kinase by neurotrophin-3 (NT-3).
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4.6 ★★★★★
Based on 29 reviews
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Product Reviews
★★★★★ 4
Overall good
Color: White
These work pretty well and adhere securely. I chose to stick on the underside lip on my nightstand in case it damages finish. I like that they pop open to remove cord when desired, although sometimes it opens when I pull on cord too hard. Overall, I think they are help and save me from rummaging around for my cord.
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Reviewed in the United States on April 14, 2026
★★★★★ 5
Great gadget
Color: White
The perfect gadget to keep my charging cord within reach. Adhesive backing allows you to place it just about anywhere. The magnetized closure keeps the cord secure but still allows for easy removal.
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Reviewed in the United States on June 1, 2026
★★★★★ 5
Easy to install, sturdy, and a must-have around the house!
Color: White, Color: White
These cord clips are the best! I have them all over my house where we have chargers. Very easy to install (just peel off a sticker), they hold nicely and have saved my from searching around for cords! The magnetic hook makes them extra sturdy. These fit so many different types of cords, a must have these days!
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Reviewed in the United States on April 4, 2026
★★★★★ 5
Great for organizing chargers
Color: White
Works exactly as shown in picture and really helped to straighten up the charging cables next to my bed.
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Reviewed in the United States on May 13, 2026
★★★★★ 5
Great shelves!
Color: Grey, Size: 55 Inch, Style: 2 Pack
This shelf is lovely--simple and modern. My handyman said it was easy to install AND made a note to buy it for his own rental units because he said the internal supports were very sturdy. Fast delivery and exactly as described--and the price is nice, too.
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Reviewed in the United States on April 17, 2026