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Description
TrkC Fc Chimera Protein, HumanProduct Specification Species Human Synonyms TrkC, Ntrk3 Accession Q96CY4 Amino Acid Sequence Cys32 Asp428, with C terminal Human IgG1 Fc
Product Specification
| Species | Human |
| Synonyms | TrkC, Ntrk3 |
| Accession | Q96CY4 |
| Amino Acid Sequence | Cys32-Asp428, with C-terminal Human IgG1 Fc CPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Expression System | HEK293 |
| Molecular Weight | 95-115kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human Fc Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Khotskaya Y B. et al. (2017). Targeting TRK family proteins in cancer. Review. 173:58-66. |
Background
The tropomyosin receptor kinase (TRK) family includes TRKA, TRKB, and TRKC proteins, which are encoded by NTRK1, NTRK2 and NTRK3 genes, respectively. Binding of neurotrophins to TRK proteins induces receptor dimerization, phosphorylation, and activation of the downstream signaling cascades via PI3K, RAS/MAPK/ERK, and PLC-gamma. TrkC functions not only as an oncogene, but also act as a tumor suppressor via a manner of dependence receptor in human malignant tumors. TrkC is a potent oncoprotein expressed in tumors derived from multiple cell lineages, and functions as an active protein tyrosine kinase by neurotrophin-3 (NT-3).
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4.2 ★★★★★
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Product Reviews
★★★★★ 5
Nice and a great value.
Size: 1 Pack, Style: USB Receiver, Color: Swift Grey
Hey, it works well. Just plug it in and you are ready to go. Only issue, minor, no light or color coding on back to indicate on or off.
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Reviewed in the United States on May 14, 2026
★★★★★ 5
Smooth and ergo nice mouse.
Size: 1 Pack, Style: USB Receiver, Color: Swift Grey
I needed this little thing quickly and got it within 2 hours of ordering. It was only an extra five bucks to get it now. Would have burned more than that in fuel. Works exactly as I would have expected. Perfect.
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Reviewed in the United States on June 11, 2026
★★★★★ 5
Simple and efficient
Size: 1 Pack, Style: USB Receiver, Color: Swift Grey
This is a dandy little item. Easy to use straight out of the box, No fancy bells and whistles.but why should a mouse try to replicate commands that are on the laptop?
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Reviewed in the United States on May 16, 2026
★★★★★ 4
Simple, Reliable, and Works Great
Size: 1 Pack, Style: USB Receiver, Color: Swift Grey
The Logitech M185 has been exactly what I needed for everyday computer use. Setup took less than a minute—just plug in the tiny USB receiver and it was ready to go. The mouse responds smoothly, tracks accurately, and feels comfortable in my hand even after several hours of use.
What I appreciate most is the reliability. The wireless connection has been stable with no noticeable lag or dropouts, and the battery life has been excellent. For browsing, office work, and general daily tasks, this mouse delivers solid performance at a very reasonable price. I'm extremely happy with it.
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Reviewed in the United States on June 11, 2026
★★★★★ 5
Great.
Size: 1 Pack, Style: USB Receiver, Color: Swift Grey
Great deal. Works great.
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Reviewed in the United States on May 24, 2026