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Description
Alexa Fluor® 647 Rat Anti-Human CD294 Antibody (S-2867)Product Specification Host Rat Antigen CD294 Synonyms Prostaglandin D2 receptor 2; Chemoattractant receptor homologous molecule expressed on Th2 cells; G protein coupled receptor 44; CRTH2; DL1R; GPR44; PTGDR2 Location Cell membrane Accession Q9Y5Y4 Clone Number S 2867 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Hu Positive Sample human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 647 Physical
Product Specification
| Host | Rat |
| Antigen | CD294 |
| Synonyms | Prostaglandin D2 receptor 2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; G-protein coupled receptor 44; CRTH2; DL1R; GPR44; PTGDR2 |
| Location | Cell membrane |
| Accession | Q9Y5Y4 |
| Clone Number | S-2867 |
| Antibody Type | Rat mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human PBMC |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Hu |
Background
CD294, also known as CRTH2, PTGDR2, or GPR44, is a seven-transmembrane G protein-coupled receptor primarily expressed on Th2 cells, eosinophils, basophils, and type-2 innate lymphoid cells (ILC2). It is involved in mediating the chemotaxis of these cells to sites of allergic inflammation, such as the asthmatic lung, and plays a role in preventing apoptosis in Th2 cells.
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