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Description
PPP2R1A Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen PPP2R1A Synonyms Serine threonine protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; PP2Aa; Medium tumor antigen associated 61 kDa protein; PP2A subunit A isoform PR65 alpha; PP2A subunit A isoform R1 alpha Immunogen Synthetic Peptide Location Nucleus, Cell membrane Accession P30153 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P, ICC Reactivity Hu, Ms, Rt, Mk Positive Sample
Product Specification
| Host | Rabbit |
| Antigen | PPP2R1A |
| Synonyms | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; PP2Aa; Medium tumor antigen-associated 61 kDa protein; PP2A subunit A isoform PR65-alpha; PP2A subunit A isoform R1-alpha |
| Immunogen | Synthetic Peptide |
| Location | Nucleus, Cell membrane |
| Accession | P30153 |
| Antibody Type | Polyclonal antibody |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms, Rt, Mk |
| Positive Sample | HeLa, Ramos, HepG2, HEK-293, NIH/3T3, RAW264.7, mouse liver, C6, COS-7 |
| Predicted Reactivity | Bv |
| Purification | Immunogen Affinity |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt, Mk |
| IHC-P | 1:500 | Hu, Ms, Rt |
| ICC | 1:500 | Hu, Ms, Rt |
Background
PPP2R1A (Protein Phosphatase 2 Regulatory Subunit A Alpha) is a core scaffold subunit of the serine/threonine phosphatase PP2A, essential for assembling the catalytic C and regulatory B subunits into an active holoenzyme that dephosphorylates hundreds of substrates, thereby governing cell-cycle progression, apoptosis, metabolism, epithelial-mesenchymal transition, and antiviral signaling; it localizes to the cytoplasm and nucleus, is frequently mutated at hotspots in ovarian, endometrial and laryngeal cancers, undergoes post-translational succinylation that switches its function from tumor suppressor to oncogene by rewiring gluconeogenesis/lipogenesis, and its expression or mutation status modulates Wnt, TGF-β, PI3K-AKT and Hippo-YAP pathways, making it a key prognostic and therapeutic target in cancer and inflammatory diseases.
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Exchange/Return Notes
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4.4 ★★★★★
Based on 26 reviews
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Product Reviews
★★★★★ 5
Great face gems!
Color: Pink
I’ve been really happy with these pink face gems and self-adhesive hair jewels. The designs are super cute and sparkly, with hearts and stars that add a fun, festive touch to Valentine’s Day makeup, festivals, raves, or any playful look. They’re easy to use since they are self-adhesive, so there’s no extra glue needed and they go on smoothly without fuss.
The gems stick well and stay in place through movement, dancing, or photos, and they feel comfortable on the skin and in the hair without itching or irritation. The pink shades are bright and eye-catching, making them perfect for girls and women who want a bit of bling.
For the quality, sparkle, and fun factor, these rhinestone stickers offer excellent value for the money. If you’re looking for a quick way to elevate your makeup or costume with glittery accents, these jewels are a great choice.
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Reviewed in the United States on February 7, 2026
★★★★★ 4
Very comfortable. Good stickiness.
Color: Gold, Color: Gold
These face/body gems are decent quality. It comes with a generous amount of gems - 3 sheets of gems in various sizes. A couple of the gems arrived with defects - the gold paint had flaked off some parts to show black underneath. Most of the gems were in good condition though. These are very lightweight and comfortable to wear. I forgot I had them on at one point and was reminded when I looked in the mirror. The adhesive did not irritate my skin at all and I wore them for a few hours. I was also able to reposition the gems several times without them loosing their staying power. I had to be careful when removing the gems from the plastic sheet because sometimes the adhesive dot would stay stuck to the plastic sheet and the gem would come off without any adhesive attached. I was able to put it back down and get it to re-stick to the adhesive and then carefully remove them together in order to apply it on my skin. Overall I'd say these are worth the purchase.
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Reviewed in the United States on February 2, 2026
★★★★★ 5
Bling that is shiny and some of the prettiest pinks - perfect for Valentine's Day!
Color: Pink, Color: Pink
For just about 5 dollars you get 3 sheets of Pink Face Gems/Hair Jewels by VVPESCA. These gems come in the prettiest pinks and have an amazing shine to them. You get your traditional gems of different sizes, but also some that come in unique hearts and stars shapes. I tried sticking them on my face and they stuck very well! I was shocked that they did not come sliding off, even with make-up on. However, when I was ready to remove them, they did come off surprisingly easy and did not leave any sort of mark or irritation. I have not tried them in my hair just yet, but based off of the high quality, I think it would work equally as well. This set of bling comes with a tweezer tool to help remove the gems from their sheets and apply them precisely where you want them. It is more helpful than I realized, as I originally tried placing them on with my fingers and it just didn't cut it as well as the tweezers. I love this set of bling! These jewels are truly great for anytime, but they are especially cute for Valentine's day. I will be wearing some that day to add a little something special!
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Reviewed in the United States on January 26, 2026
★★★★★ 5
Cute, with effective self adhesive
Color: Gold, Color: Gold
These are super cute.
I’ll start with the packaging:
The kit comes all together in a plastic pouch. There are three sheets of gold stud stickers, and a separately packaged pair of application tweezers. The sheets are individually packaged with a thin cardboard backing to keep them from wrinkling, and they themselves are stuck onto a transparent sheet of plastic.
They are secured with tiny plastic double sided stickers on the back, similar to double sided tape. Note: sometimes the stud pulls right off the sticker, but you can grab that bad boy gently with the tweezers, peel it off, and stick it right back on without losing any adhesive property.
I decided to just experiment with them to see how they work. I was able to move the studs from one part of my face to another, testing out what different piercings might look like, and on the third location change I just left them there and they stayed perfectly fine without falling off. So don’t let the occasional sticker pulling away from the stud concern you; the self adhesive is actually pretty legit!
I know I look like I haven’t slept in three years, but including a picture after I had already moved them around a few times so you can see how they managed to keep their stickiness.
I plan to do an elaborate makeup look and utilize them for it tomorrow so I might come back and add cooler pictures of that as well!
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Reviewed in the United States on January 23, 2026
★★★★★ 5
Yummy
My dog loved them!
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Reviewed in the United States on March 8, 2026
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