SKU: 48598833832

Alexa Fluor® 647 Rat Anti-Mouse CD20 Antibody (S-R497)

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Description

Alexa Fluor® 647 Rat Anti-Mouse CD20 Antibody (S-R497)Product Specification Host Rat Antigen CD20 Synonyms B lymphocyte antigen CD20; B cell differentiation antigen Ly 44; Lymphocyte antigen 44; Membrane spanning 4 domains subfamily A member 1; Ly 44; Ms4a2; Ms4a1 Location Cell membrane Accession P19437 Clone Number S R497 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Ms Positive Sample BALB c mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 647

Product Specification


Host Rat
Antigen CD20
Synonyms B-lymphocyte antigen CD20; B-cell differentiation antigen Ly-44; Lymphocyte antigen 44; Membrane-spanning 4-domains subfamily A member 1; Ly-44; Ms4a2; Ms4a1
Location Cell membrane
Accession P19437
Clone Number S-R497
Antibody Type Rat mAb
Isotype IgG2b,k
Application FCM
Reactivity Ms
Positive Sample BALB/c mouse splenocytes
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 647
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

CD20 is a 33-37 kDa non-glycosylated phosphoprotein expressed on the surface of B cells from the pre-B cell stage through maturity, but absent on plasma cells. It belongs to the MS4A protein family and has four transmembrane domains, one intracellular domain, and two extracellular loops. CD20 is believed to facilitate calcium influx, which is essential for B cell activation and proliferation. Although its exact biological function is not fully elucidated, studies suggest it plays a role in B cell receptor signaling and may act as a calcium channel. CD20 is a key therapeutic target for B cell malignancies and autoimmune diseases, as it is expressed on various B cell cancers and its targeting can induce cell death through mechanisms like complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity.

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Exchange/Return Notes
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SKU: 48598833832

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4.0 ★★★★★
Based on 10 reviews
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Verified Purchase
Paul Andreini
Port Orchard, US
★★★★★ 5
A Beautiful Timepiece at an Awesome Price!!
Color: Grey, Color: Grey
I have lusted after this watch for four months. I first tried on a similar model (stainless steel band with a green face) in a local jewelry shop (Spitz Jewlers, Walnut Creek, CA, USA). It was "love at first sight," even if I didn't love the white lines on the face from 12-6 and 3-9. At the time, the MSRP was $775. The MSRP has since increased to $795. But I bought this beauty on Amazon.com for only $524.99; after applying the cash-back from my Prime credit card, this watch costs only $498.75. This was "the offer that I could not refuse," to quote from "The Godfather." Accuracy could be better: after only a few days, it is now 7 seconds behind my phone (to which I set my new watch). But I don't really care about that all that much. This is why I rated "accuracy" at 4 stars, but my overall review is 5 stars. My video shows the date changing suddenly at 11:59:59pm, just how I want it; in another photo, you can see that my Seiko changes the date more slowly, which I do not like. This watch is absolutely phenomenally beautiful. If you're on the fence over whether to make this purchase, then I would say "go for it!" You will not find a prettier, more accurate watch at a lower price in ANY store in the entire USA.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 28, 2023
P
Verified Purchase
pradeepkanth
San Leandro, US
★★★★★ 4
Classy and sporty. Great value!
Color: Grey, Color: Grey
Excellent watch for the price. Looks sporty and dressy. More towards dress watch. Blue is dynamic. Strongly recommend blue for sporty feel. I was thinking of aqua terra. This come close to it with a price less than what i would have paid my state tax for omega aqua terra. My only concern is bracelet which i feel kind of OK. Better bracelet design would have made this watch much superior. 21 lug width is awful. Other than that, nothing to complain.
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Reviewed in the United States on July 13, 2020
T
Verified Purchase
Tim Shepherd
Whiting, US
★★★★★ 5
Stunning Gentleman's Watch
Color: Grey
This is my second Tissot watch. It's quite stunning in person. The online photos don't do it justice. It has the look and feel of a much more expensive gentleman's watch which makes this purchase a great bargain. Tissot is a great reliable Swiss made watch brand. My first Tissot watch which is probably more than 20 years old still runs great. Very pleased with this purchase.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on October 16, 2025
L
Verified Purchase
L.Lopez
Phoenix, US
★★★★★ 5
Good Tissot Watch
Color: Grey
Arrived on time, in its original box, include a 2 year international warranty, into the box include a book with the Tissot brand history in Switzerland. Algo a second book with a whole catalog of Tissot watches men and women. The watch looks better when you put in on your wrist. The “naval” blue really gives the clock a classy look. The stainless steel workmanship is really good, the metal is bright and perfectly polished. The metal wristband quality is very good, did not have any problem to adjust the size , I went to my preferred clock workshop for this job, they extracted a few pieces of the band to fit to my small wrist size. Have to get used to the butterfly latch, but after a few days, now I learned to open and close it without any effort. The clock it’s very accurate, I’ve been using my Tissot for near a month and it just increased a few seconds per week. I do the setup and check accuracy with my pc clock. In short, It”s a good value watch, nice, good looking, accurate.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 1, 2021
D
Verified Purchase
Dan Panetti
Natrona Heights, US
★★★★★ 5
Look and feel awesome!
Size: 11.5, Color: Optic White/Opti
These are awesome shoes - look great really, really white and clean! Love how comfortable they are - and soooo light. I was a little worried they'd get dirty easily, but I've been able to keep them clean. Fit as expected. If you're looking for a great, comfortable, and affordable shoe, check these out!
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Reviewed in the United States on December 4, 2025

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