SKU: 47953614147

TAG1/Contactin 2 His Tag Protein, Mouse

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Description

TAG1/Contactin 2 His Tag Protein, MouseProduct Specification Species Mouse Synonyms Axonal glycoprotein TAG 1; axonin 1 cell adhesion molecule; Axonin 1; AXT; CNTN2; contactin 2 (axonal); contactin 2 (transiently expressed); Contactin2; Contactin 2; DKFZp781D102; FLJ37193; MGC157722; TAG1; TAG 1; TAX; TAX1; TAX 1; TAX1FLJ42746; Transient axonal glycoprotein 1; transiently expressed axonal glycoprotein Accession Q61330 Amino Acid Sequence Gln31 Ser1014, with C terminal His Expression System

Product Specification


Species Mouse
Synonyms Axonal glycoprotein TAG-1; axonin-1 cell adhesion molecule; Axonin-1; AXT; CNTN2; contactin 2 (axonal); contactin 2 (transiently expressed); Contactin2; Contactin-2; DKFZp781D102; FLJ37193; MGC157722; TAG1; TAG-1; TAX; TAX1; TAX-1; TAX1FLJ42746; Transient axonal glycoprotein 1; transiently-expressed axonal glycoprotein
Accession Q61330
Amino Acid Sequence Gln31-Ser1014, with C-terminal His
Expression System HEK293
Molecular Weight 110-130kDa (Reducing)
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer 50mM Tris,0.1M NaCl,0.1M Arg, pH8.0.
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.Wolfer, D. and R. J. Giger (1994) Swissprot Accession # Q61330. 2.Hasler, T.H. et al. (1993) Eur. J. Biochem. 211:329. 3.Karagogeos, D. (2003) Front. Biosci. 8:s1304.

Background

Contactin-2 is also known as CNTN2, TAX1 (transiently-expressed axonal glycoprotein), TAG1 (transient axonal glycoprotein), and axonin-1, and is a member of the immunoglobulin superfamily. In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region.As a neural cell adhesion molecule expressed by a subset of neuronal populations in the developing CNS and PNS, CNTN2 mediates cell-cell interactions either via homophilic, or heterophilic contacts with various adhesion molecules including NgCAM, NrCAM, NCAM and neurocan. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.

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SKU: 47953614147

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