Pay in installments of $61.25 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 1 - Sep 6
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Biotinylated Fc γ RI/CD64 His&Avi Tag Protein, MouseProduct Specification Species Mouse Synonyms FCGR1A,FCG1,FCGR1,IGFR1,CD64,CD64A,FCRI Accession P26151 Amino Acid Sequence Glu25 Pro297, with C terminal His+Avi tag Expression System HEK293 Molecular Weight 43 53kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag Avi Tag, His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4. Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in
Product Specification
| Species | Mouse |
| Synonyms | FCGR1A,FCG1,FCGR1,IGFR1,CD64,CD64A,FCRI |
| Accession | P26151 |
| Amino Acid Sequence | Glu25-Pro297, with C-terminal His+Avi tag |
| Expression System | HEK293 |
| Molecular Weight | 43-53kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4. |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1. Joan Cid, Reyes Aguinaco, Rafael Sánchez, Graciano García-Pardo, Andreu Llorente: Neutrophil CD64 expression as marker of bacterial infection: A systematic review and meta-analysis. Journal of Infection, Volume 60, Issue 5, May 2010, Pages 313-319. |
Background
Fc γ RI, also known as CD64, is an integral cell membrane glycoprotein that transmits activation signals through the associated Fc R γ chain, commonly referred to as Fc-γ receptor 1 (Fc γ RI), and the high affinity recognition of IgG by Fc γ RI allows it to trigger effector responses at lower low IgG concentrations in early immune responses. After binding to IgG, CD64 interacts with an accessory chain called the common gamma chain, which has an ITAM motif necessary for triggering the cell and for activation. It is usually constitutively expressed on monocytes and macrophages, and can be induced by neutrophils and eosinophils, where its expression is upregulated in bacterial infections and sepsis.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy