SKU: 45819483289

Alexa Fluor® 488 Rat Anti-Mouse CD25 (IL-2Rα) Antibody (S-3558)

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Description

Alexa Fluor® 488 Rat Anti-Mouse CD25 (IL-2Rα) Antibody (S-3558)Product Specification Host Rat Antigen CD25 Synonyms Interleukin 2 receptor subunit alpha; IL 2 receptor subunit alpha; IL 2 RA; IL 2R subunit alpha; IL2 RA; p55; Il2r; Il2ra Location Membrane Accession P01590 Clone Number S 3558 Antibody Type Rat mAb Isotype IgG1, Application FCM Reactivity Ms Positive Sample BALB c mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer

Product Specification


Host Rat
Antigen CD25
Synonyms Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; p55; Il2r; Il2ra
Location Membrane
Accession P01590
Clone Number S-3558
Antibody Type Rat mAb
Isotype IgG1,λ
Application FCM
Reactivity Ms
Positive Sample BALB/c mouse splenocytes
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 488
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1.25μl per million cells in 100μl volume Ms

Background

CD25, also known as the interleukin-2 receptor alpha chain (IL2RA), is a type I transmembrane glycoprotein that plays a crucial role in the immune system. It is primarily expressed on the surface of activated T cells and regulatory T cells (Tregs). CD25 is a key component of the high-affinity IL-2 receptor complex, which also includes the IL-2 receptor beta and gamma chains. By itself, CD25 can bind IL-2 with low affinity, but when combined with the beta and gamma chains, it forms a high-affinity receptor that initiates intracellular signaling pathways such as MAPK and JAK/STAT. This receptor complex is essential for the proliferation and activation of T cells, as well as the regulation of immune tolerance by controlling the activity of Tregs. Mutations in the IL2RA gene can lead to deficiencies in IL-2 receptor function, highlighting its importance in maintaining immune homeostasis.

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SKU: 45819483289

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Amazon Customer for Reviews
Lake Worth, US
★★★★★ 5
Huge tent
Size: 10 Person
This tent is so easy to out together, took maybe 10 minutes and everyrhing was so easy! It just popped up and was perfect for my family. Ther was so much space that we never had any issues about being squeezed together. Highly recommend!
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Reviewed in the United States on June 2, 2026
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vj
Waukegan, US
★★★★★ 5
Large, easy to set up
Size: 10 Person
Better than anticipated! Loved the size, the ease with which it was put up, and the height! Not a fan of how the "room divider" divides, but it works. Despite the photos, for some reason I was expecting a little more separation, but you have to go through the first 'room' to access the second. Other tents that I looked at that had 2 rooms had 2 side-by-side entrances. Still, very pleased with the tent overall. Did not get to test the water resistance, luckily, but it does seem like a good, sturdy tent that is easy to put up, even with three 7 year old boys running around the camp site.
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Reviewed in the United States on May 21, 2026
K
Verified Purchase
KR
Waukegan, US
★★★★★ 4
Easy set up
Size: 10 Person
The tent was easy to set up. The instructions were easy to understand. It was nice to lay out the tent and clip the poles into place. Easy to set up for one person. All the zippers work and looks to be well made. Hopimg it will.last quote a while. I'm 6'3" and had plenty of space to stand. Lots of room on the inside. Looking forward to using this tent a lot.
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Reviewed in the United States on May 4, 2026
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SLOMillie
Louisville, US
★★★★★ 5
I can put it up by myself!!!
Size: 6 Person
So easy to use! Roomy and so well made!
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Reviewed in the United States on June 4, 2026
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Ken
Dallas, US
★★★★★ 1
No Good
Size: 6 Person
Brand new screen netting on door and windows had small holes thus allowing mosquitoes in. Unfortunately the return window passed but due to weather we just got to try it out last week. Also floor had pin holes first use which I think after several uses will develope bigger holes. Very thin material. Also came with no setup instructions but that was easy to figure out. Like the fast setup that’s it. I may have gotten someone else’s return ???
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Reviewed in the United States on May 30, 2026

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