SKU: 39891321418

Pacific Blue Armenian hamster Anti-Mouse CD3 Antibody (S-R491)

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Description

Pacific Blue Armenian hamster Anti-Mouse CD3 Antibody (S-R491)Product Specification Host Armenian hamster Antigen CD3 Synonyms T cell surface glycoprotein CD3 zeta chain; T cell receptor T3 zeta chain; Cd3z; Tcrz; Cd247 Location Cell membrane Accession P24161 Clone Number S R491 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Pacific Blue Physical Appearance Liquid Storage Buffer PBS, 1%

Product Specification


Host Armenian hamster
Antigen CD3
Synonyms T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; Cd3z; Tcrz; Cd247
Location Cell membrane
Accession P24161
Clone Number S-R491
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Pacific Blue
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

CD3, also known as the cluster of differentiation 3, is a protein complex found on the surface of T cells, playing a crucial role in the immune system. It consists of four distinct chains: CD3γ, CD3δ, CD3ε, and CD3ζ. These chains form a complex that associates noncovalently with the T-cell receptor (TCR) to form the TCR complex, which is essential for recognizing antigens presented by major histocompatibility complex (MHC) molecules. When the TCR binds to an antigen-MHC complex, the CD3 complex transmits signals into the T cell, initiating a cascade of intracellular events that lead to T cell activation, proliferation, and differentiation. This process is vital for the immune response against pathogens and abnormal cells. CD3 is also involved in T cell development and maturation in the thymus. Given its central role in T cell function, CD3 is a key target in immunotherapy for diseases such as cancer and autoimmune disorders.

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Exchange/Return Notes
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SKU: 39891321418

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4.6 ★★★★★
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Scouter Doug
Carnegie, US
★★★★★ 5
I Gambled - Works So Far after 2 Months
I used this as a replacement starter for a 2008 CRV. Quick answer, it works so far and sounds fine. It replaced a fairly newly rebuilt OEM starter - "factory rebuilt in the USA" - so much for them- very dissapoiinting. When I looked for replacement EVERY starter I looked at locally had horrible reviews online with consistency issues - some worked, some didn't. I figured, if that's the case, buy the cheapest one. So far this Boatrip is the real deal - beautifully machined and went in just like the original. I went ahead and took off the intake manifold - it was a huge job for me. I ended up tearing my throttle body gasket and didn't replace it. Now I have a fast idle check engine light. So, I'll need to take that part apart and replace the gasket. I guess it's sucking air and throwing off the idle speed. otherwise, the YouTube videos really helped on the repair. I hope I don't have to do it again. Good luck!
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Reviewed in the United States on September 6, 2025
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Kayla
Lexington, US
★★★★★ 5
Good 👍
Works just like oem
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Reviewed in the United States on February 26, 2026
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Whorley boi
West Palm Beach, US
★★★★★ 4
Price
Perfect fit at a great price
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Reviewed in the United States on March 18, 2026
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Jeffrey Hodge
Battle Creek, US
★★★★★ 5
Good luck
So far so good,fit perfectly but was a real bitch to replace on a 09 Crv. Tried from underneath but couldn’t get to the rear bolt, so I had to go from the top. Poor engineering on Hondas part.
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Reviewed in the United States on March 29, 2026
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Claribet Colón Pagán
Port Orchard, US
★★★★★ 5
Bueno
Cumplió su propósito
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Reviewed in the United States on April 16, 2026

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