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Description
Biotinylated Fc γ RIIIa/CD16a(F176) Avi&His Tag Protein, HumanProduct Specification Species Human Synonyms Fc RIIIa, CD16a, FcR 10 Accession P08637 1 Amino Acid Sequence Gly17 Gln208, with C terminal Avi & 8*His Tag GMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKNVSSETVNITITQGLAVSTISSFFPPGYQGGGSGLNDIFEAQKIEWHEHHHHHHHH Expression System HEK293 Molecular Weight 45 53kDa Purity >95% by SDS PAGE
Product Specification
| Species | Human |
| Synonyms | Fc γ RIIIa, CD16a, FcR-10 |
| Accession | P08637-1 |
| Amino Acid Sequence | Gly17-Gln208, with C-terminal Avi & 8*His Tag GMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKNVSSETVNITITQGLAVSTISSFFPPGYQGGGSGLNDIFEAQKIEWHEHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 45-53kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Nimmerjahn F. et al. (2006) Fcgamma receptors: old friends and new family members. Immunity J. 24(1): 19-28. |
Background
Fc gamma RIIIa is a low/intermediate affinity receptor for polyvalent immune-complexed IgG. It is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody-dependent cytotoxicity and clearance of immune complexes. In humans, it is a 50-70 kDa type I transmembrane activating receptor expressed by NK cells, T cells, monocytes, and macrophages. A single nucleotide polymorphism creates high binding (V176) and low binding (F176) forms that, when homozygous, may influence susceptibility to autoimmune diseases or response to therapeutic IgG antibodies. Aberrant expression or mutations of CD16a is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia.
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4.4 ★★★★★
Based on 28 reviews
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Product Reviews
★★★★★ 5
HEALTHY HAIR
Scent: Keratin
It makes my hair feel, soft, manageable, non frizzy, healthy. Shiny, curl definition.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 24, 2026
★★★★★ 3
That it works
Scent: Damaged Hair
I just tried it i can't commend until I keep using it but my hair feels softer
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Reviewed in the United States on February 5, 2026
★★★★★ 5
Best Stuff Non Greasy Super Shine
Scent: Argan Oil
Wow! This product blew my mind! I have fine hair, bleached blond and this product made my hair soooo shiny nothing has ever done that! The fragrance is minimal but pleasant. This improved the condition of my hair immediately and I didn't even leave it on very long. No greasy feel afterward which is important with my fine hair. I bought another for daughter's frizzy hair she was impressed.
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Reviewed in the United States on April 20, 2026
★★★★★ 5
Just a great product
Scent: Curly
Honestly I’ve tried plenty of hair mask before and none of them can do what this one does! My hair is so hydrated after 2 uses! When I wash it out my hair actually maintains the water and it’s so easy to comb through and style 10/10
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Reviewed in the United States on June 8, 2026
★★★★★ 5
Fantastic heat protection
Color: Biotin, Color: Biotin
I highly recommend this heat protecting spray because it has truly helped my hair become healthier. I blow dry and straighten my hair so much and I rarely use to protect it so it became quite damaged over time. I've been using this for roughly 3 weeks now and my hair is becoming healthier, shinier and growing so much better because it's not breaking or getting dried out. I like the smell of the spray - it's really nice. It's not sticky and doesn't leave any residue in my hair. And it doesn't leave my hair stiff like it's got hair spray in it. This spray stops my hair from going all frizzy including when I'm hot or it's humid. It also protects my hair colour too. I would recommend this.
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Reviewed in the United States on June 6, 2024