SKU: 33891626524

SEZ6 Recombinant Rabbit mAb,PBS Only(SDT-2097-737)

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Description

SEZ6 Recombinant Rabbit mAb,PBS Only(SDT-2097-737)Product Specification Host Rabbit Antigen SEZ6 Synonyms Seizure protein 6 homolog; SEZ 6; hSEZ 6 Immunogen Recombinant Protein Location Cell membrane Accession Q53EL9 Clone Number SDT 2097 737 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Positive Sample H69 Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of

Product Specification


Host Rabbit
Antigen SEZ6
Synonyms Seizure protein 6 homolog; SEZ-6; hSEZ-6
Immunogen Recombinant Protein
Location Cell membrane
Accession Q53EL9
Clone Number SDT-2097-737
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IHC-P
Reactivity Hu
Positive Sample H69
Purification Protein A
Concentration 1 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000-1:10000 Hu
IHC-P 1:2000 Hu

Background

SEZ6 (Seizure-related gene 6) is a type I transmembrane glycoprotein (~110 kDa) composed of five short consensus repeat (SCR) domains, three CUB domains, a single transmembrane segment and a short cytoplasmic tail that is predominantly expressed in the central nervous system, where it acts as a critical trafficking chaperone for kainate receptor subunits GluK2/3, ensuring their proper N-glycosylation (including the HNK-1 epitope), post-ER export and surface localization to regulate synaptic connectivity, long-term potentiation and dendritic arbor balance, and is sequentially cleaved by BACE1 and γ-secretase to release a soluble ectodomain whose CSF level serves as a direct pharmacodynamic read-out of BACE1 inhibition, while in neuroendocrine neoplasms its selective over-expression is exploited as an ADC target for therapies against small-cell lung cancer and related tumors.

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SKU: 33891626524

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Zealfi
Whiting, US
★★★★★ 5
Well designed, well built.
Size: 25in
The stick facilitates powerful, long distance throws. The ball makes a light whistling noise (to help your dog track the ball) through the air, flys far, and has held up well. I live in an area with mountain lions, and they often hunt at night, so I haven’t taken advantage of the glow-in-the-dark feature.
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Reviewed in the United States on February 28, 2026
K
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Keith K
Cuba, US
★★★★★ 5
Perfect for Blind Dogs, Fun and Durable
Size: 2-pack, Style: Duo
My blind dog loves these Chuckit! sniff balls. She can easily sniff them out and plays fetch with them for 20 minutes a day, even running up and down the stairs. The balls are durable, bounce well, and the bacon and peanut butter scent keeps her engaged. I do wish Chuckit! would bring back the version with a tone so we could play fetch outside more easily. Overall, a fantastic toy for dogs that rely on scent and a fun way to keep them active.
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Reviewed in the United States on February 14, 2026
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S L
Dallas, US
★★★★★ 5
My Golden Loves
Size: 2-pack, Style: Duo
My 8 month old Golden Retriever loves these. It is also one of the few products she cannot destroy. They smell as described and she loves to chew them and play fetch when. She can chew these easily without destroying them. Overall good value for the money for my Golden
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Reviewed in the United States on January 2, 2026
A
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Amazon Customer
Phoenix, US
★★★★★ 5
My dogs are obsessed with this ball
Size: 2-pack, Style: Duo
Great quality! I have 2 boxers that love it and the ball is still intact
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Reviewed in the United States on January 31, 2026
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Dianna H
Dallas, US
★★★★★ 5
Not Scented, but Dog Approved
Size: 2-pack, Style: Duo
They don't smell like peanut butter or bacon. But our dogs still love them.
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Reviewed in the United States on August 31, 2025

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