SKU: 77439014036

Alexa Fluor® 488 Armenian hamster Anti-Mouse TCR γ/δ Antibody (S-R525)

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Description

Alexa Fluor® 488 Armenian hamster Anti-Mouse TCR γ/δ Antibody (S-R525)Product Specification Host Armenian hamster Antigen TCR Location Cell membrane Accession 110066 110067 Clone Number S R525 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 2

Product Specification


Host Armenian hamster
Antigen TCR γ/δ
Location Cell membrane
Accession 110066、 110067
Clone Number S-R525
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 488
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

TCR γ protein is a key component of the γδ T cell receptor (TCR), which is a heterodimer comprising TCRγ and TCRδ chains. Unlike the αβ TCR, which primarily recognizes peptide antigens presented by MHC molecules, the γδ TCR can identify a diverse range of antigens in an MHC-independent manner. This includes small phosphorylated non-peptide antigens, such as those produced by cellular pathogens and cancers. The γδ TCR is associated with three CD3 dimeric subunits—CD3εγ, CD3εδ, and CD3ζζ—forming an octameric γδ TCR–CD3 complex. This complex plays a crucial role in the immune response by triggering the phosphorylation of ITAMs within the cytoplasmic tails of CD3 subunits upon antigen engagement, initiating downstream signaling events. The γδ TCR–CD3 complex is an attractive target for cancer immunotherapy due to its unique properties and effector functions. TCR δ protein is a component of the γδ T cell receptor (TCR), forming a heterodimer with TCR γ chain. This γδ TCR is expressed on γδ T cells, which are a unique subset of T cells with both adaptive and innate immune characteristics. Unlike αβ TCRs that primarily recognize peptide antigens presented by MHC molecules, γδ TCRs can recognize a diverse range of antigens in an MHC-independent manner. TCR δ, along with TCR γ, undergoes somatic recombination of V, D, and J gene segments to generate diversity. The γδ TCR-CD3 complex, which includes TCR γ, TCR δ, and CD3 subunits, plays a crucial role in antigen recognition and T cell activation. Upon antigen binding, the complex triggers the phosphorylation of ITAMs in the CD3 subunits, initiating downstream signaling pathways that lead to T cell proliferation, differentiation, and effector functions. This makes the γδ TCR-CD3 complex an attractive target for cancer immunotherapy, as it can provide broad protective immune responses against various infections and tumors.

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SKU: 77439014036

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Paola
Dallas, US
★★★★★ 5
Buena compra
Color: Apricot, Size: 14-Inch
Calidad, Color, espacio.
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Reviewed in the United States on May 1, 2026
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Vivian
Lexington, US
★★★★★ 3
Gorgeous, but some big downsides
Color: Pink-upgrade, Size: 14 Inch
I wanted to like this bag SO BADLY. I’ve owned other backpacks by this brand and they have never disappointed. This one though, was a close miss. The color is absolutely GORGEOUS and I almost kept it for that reason alone. However, two big things made me return it: 1) The inside is no longer padded. If you had purchased older Golf Supags backpacks, the interior had padding to help the backpack keep its shape and not slouch over on the floor. That’s gone, so this one does flop over a little. But the big deal breaker: 2) holy cannoli, these straps are WAY too long! On the shortest length, the backpack is still hanging almost halfway down my back. It looks weird, but it’s also not ergonomically good for your back. The actual strap part (with padding) is so far back that the thin seatbelt adjustable material is the only thing on my shoulders. Super awkward. I’m not necessarily a small person either, so I shudder to think what this would look like on someone more petite than me.
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Reviewed in the United States on July 15, 2025
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STEPHANIE
West Palm Beach, US
★★★★★ 1
Flimsy and cheap
Color: Apricot, Size: 14-Inch
This is the second time I bought a purse online... First was on temu ... Expected to be trash and it was... So I bought this one... And idk what's worse, the temu purse or this one.. only buying them in person from now on unless Its 100% obviously sturdy and of good quality. The fabric and entire purse itself is cheap thin fabric .. not only does it feel cheap it looks cheap. I'm not one to write comments but I'd return it if I wasn't so damn lazy... It feels like the play purses your parents would give you as a kid. Not worth the money. I guess it has pockets, but I feel like my things would be sitting on the floor even though my purse is a barrier and feels like my belongings are not protected in the slightest... Especially not a laptop as advertised.
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Reviewed in the United States on April 5, 2025
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swissmiss
Fort Morgan, US
★★★★★ 5
Beautiful and Well Made
Color: Royal Blue, Size: Small
Remarkable and well made top. It fits perfectly, is super soft and of substantial fabric. The color (royal blue) is vibrant and looks like the picture. It is made and feels like a much more expensive top you would find in an upscale shop. It wears well and you are never hot, just wonderful.
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Reviewed in the United States on May 29, 2026
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★★★★★ 5
Best white tshirt ever! Will have to buy more
Color: White, Size: Medium
Top is great, better than the expensive designer top I bought. Fabric is so very soft, not super thin and just the right size. I bought a med and it fit perfectly, just right under a jacket or separate. It’s pure white with some stretch if you want a. Lose fit.
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Reviewed in the United States on May 17, 2026

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