Pay in installments of $48.75 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 3 - Sep 8
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Alexa Fluor® 700 Mouse Anti-Human Granzyme B Antibody (S-3342)Product Specification Host Mouse Antigen Granzyme B Synonyms C11; CTLA 1; Cathepsin G like 1 (CTSGL1); Cytotoxic T lymphocyte proteinase 2 (Lymphocyte protease); Fragmentin 2; CGL1; CSPB; CTLA1; GRB; GZMB Location Secreted Accession P10144 Clone Number S 3342 Antibody Type Mouse mAb Isotype IgG1,k Application ICFCM Reactivity Hu Positive Sample Human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 700 Physical Appearance
Product Specification
| Host | Mouse |
| Antigen | Granzyme B |
| Synonyms | C11; CTLA-1; Cathepsin G-like 1 (CTSGL1); Cytotoxic T-lymphocyte proteinase 2 (Lymphocyte protease); Fragmentin-2; CGL1; CSPB; CTLA1; GRB; GZMB |
| Location | Secreted |
| Accession | P10144 |
| Clone Number | S-3342 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | ICFCM |
| Reactivity | Hu |
| Positive Sample | Human PBMC |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 700 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| ICFCM | 5μl per million cells in 100μl volume | Hu |
Background
Granzyme B is a 32-kDa serine protease stored in the cytolytic granules of cytotoxic T lymphocytes and natural killer cells, whose immune function centers on perforin-assisted translocation into target cells where it directly cleaves and activates pro-apoptotic substrates such as procaspase-3, Bid and PARP, thereby igniting both caspase-dependent and caspase-independent mitochondrial apoptosis pathways to eliminate virus-infected or malignant cells.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy