Pay in installments of $27.50 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 21 - Sep 26
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Mouse Anti-Human CD70 Antibody (S-2898)Product Specification Host Mouse Antigen CD70 Synonyms CD70 antigen; CD27 ligand (CD27 L); Tumor necrosis factor ligand superfamily member 7Imported; CD27L; CD27LG; TNFSF7 Location Cell membrane Accession P32970 Clone Number S 2898 Antibody Type Mouse mAb Isotype IgG3,k Application FCM Reactivity Hu Positive Sample U266B1 Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4
Product Specification
| Host | Mouse |
| Antigen | CD70 |
| Synonyms | CD70 antigen; CD27 ligand (CD27-L); Tumor necrosis factor ligand superfamily member 7Imported; CD27L; CD27LG; TNFSF7 |
| Location | Cell membrane |
| Accession | P32970 |
| Clone Number | S-2898 |
| Antibody Type | Mouse mAb |
| Isotype | IgG3,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | U266B1 |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 1:200 | Hu |
Background
CD70, also known as CD27 ligand, is a type Ⅱ transmembrane protein that plays a crucial role in the immune system. It is primarily expressed on antigen - presenting cells (APCs) such as dendritic cells, macrophages, and B cells, as well as on activated T cells. CD70 interacts with its receptor CD27, which is mainly found on T cells, B cells, and natural killer (NK) cells. This interaction provides important co - stimulatory signals that promote T cell activation, proliferation, and differentiation, and also enhances B cell and NK cell functions. Additionally, CD70 is involved in the regulation of immune responses, including the maintenance of immune homeostasis and the induction of immune - mediated tumor cell killing. Abnormal expression of CD70 has been associated with various diseases, such as autoimmune disorders and certain types of cancers. Therefore, CD70 is considered a promising target for the development of immunotherapies.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy