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Description
Bovine RHOXF1 Recombinant Rabbit mAb (S-1764-118)Product Specification Host Rabbit Antigen Bovine RHOXF1 Synonyms Rhox homeobox family member 1 Immunogen Recombinant Protein Location Nucleus Clone Number S 1764 118 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Bv Positive Sample bovine testis Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability &
Product Specification
| Host | Rabbit |
| Antigen | Bovine RHOXF1 |
| Synonyms | Rhox homeobox family member 1 |
| Immunogen | Recombinant Protein |
| Location | Nucleus |
| Clone Number | S-1764-118 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Bv |
| Positive Sample | bovine testis |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:2000 | Bv |
| IHC-P | 1:500 | Bv |
Background
Bovine RHOXF1 is a ~20.5 kDa reproductive-homeobox transcription factor that shuttles between nucleus and cytoplasm in testicular and mammary cells, where it preferentially binds promoters of fertility-related and metabolic genes—such as ACADVL, IRF6, APOA5 and AKT3—and generally represses their transcription, thereby modulating lipid catabolism, β-casein synthesis and milk-component secretion; in cattle populations, natural SNPs that disrupt its DNA-binding motif are associated with significant differences in milk-fat and protein yield, while in vitro studies indicate that RHOXF1 silencing accelerates apoptosis and reduces proliferation of bovine mammary epithelial cells, collectively pointing to a central, dose-sensitive role in coordinating male germ-cell maturation with lactation physiology.
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