SKU: 20410436595

Human IGFBP5 Protein, His Tag

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Description

Human IGFBP5 Protein, His TagProduct Specification Species Human Synonyms Insulin like growth factor binding protein 5, IBP 5, IGF binding protein 5, IGFBP 5, IBP5 Accession P24593 Amino Acid Sequence Protein sequence (P24593, Leu21 Glu272, with C His Tag)

Product Specification


Species Human
Synonyms Insulin-like growth factor-binding protein 5, IBP-5, IGF-binding protein 5, IGFBP-5, IBP5
Accession P24593
Amino Acid Sequence

Protein sequence (P24593, Leu21-Glu272, with C-His Tag) LGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE

Expression System HEK293
Molecular Weight Predicted MW: 30.3 kDa Observed MW: 40 kDa
Purity >95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Physical Appearance Lyophilized powder
Storage Buffer

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.

Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

Insulin-like growth factor-binding protein 5 (IGFBP5) is a key member of the IGFBP family, which regulates the bioavailability and activity of insulin-like growth factors (IGFs). Expressed in various tissues, IGFBP5 modulates cell proliferation, differentiation, and apoptosis through IGF-dependent and IGF-independent mechanisms. It interacts with extracellular matrix components and influences signaling pathways like MAPK and PI3K. IGFBP5 is implicated in physiological processes (e.g., bone development, wound healing) and pathologies, including cancer and fibrosis.

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SKU: 20410436595

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4.5 ★★★★★
Based on 18 reviews
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Verified Purchase
ChrisKindle
New York, US
★★★★★ 5
Little Dog LOVED It
Item Shape: Ring, Size: 6 Count (Pack of 1)
These are very small but perfect for little dogs. My terrier mix is 17 lbs and got frightened by his bully stick hitting the floor several years ago. Since then he has refused to chew on every kind of chew I've bought him, despite using every method of convincing him they're safe. This turkey tendon ring was the FIRST chew he's been willing to chew! He was trembling through the first few nibbles and then devoured the whole thing within 20 mins. I could not be happier and will buy more when he finishes this bag.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 10, 2026
S
Verified Purchase
Sam B
Belleville, US
★★★★★ 5
Your dog will thank you
Item Shape: Ring, Size: 6 Count (Pack of 1), Item Shape: Ring, Size: 6 Count (Pack of 1)
My dog is obsessed!! I don't even think obsessed is the right word, like she will take a turkey ring over going to the dog park! She has a sensitive stomach and I love that these turkey treats don't give her diarrhea or gas. I work from home so when I have an important meeting or something that requires my undivided attention, I give her one of these and it keeps her occupied for about 30 to 40 mins. They are a bit pricey but my little princess is worth it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 28, 2026
R
Verified Purchase
Rosie Dusovic
Waukegan, US
★★★★★ 5
Great treats
Item Shape: Ring, Size: 6 Count (Pack of 1)
My puppy LOVES these! He can be in the other room and when I go to open the bag hes right behind me. He will do anything for these!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 24, 2026
R
Verified Purchase
Robin C.
Lexington, US
★★★★★ 4
Good for puppies.
Item Shape: Ring, Size: 6 Count (Pack of 1)
Puppies chew on, very good for teething. Older dogs will try to eat them whole.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 24, 2026
M
Verified Purchase
Madeline Reed
New York, US
★★★★★ 5
Great for little dogs
Item Shape: Ring, Size: 1 Count (Pack of 4)
My little guy loves these. He gets them for special occasions and he gets so excited
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 20, 2026

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