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Description
Pure Encapsulations > Pregnenolone 10 mg - 180 Capsules PATIENT ONLYHormone precursor to support mood and memory BENEFITS & FEATURES Supports memory Promotes positive mood Natural precursor to over 150 steroid hormones Available in 10 mg and 30 mg capsules Made with high quality vegan ingredients backed by verifiable science Please see the Supplement Facts tab for a full listing of the Ingredients in this product. In summary, it contains: Pregnenolone (3 beta hydroxy 5 pregnen 20 one). Supplement Facts Suggested Use
Hormone precursor to support mood and memory
BENEFITS & FEATURES
- Supports memory‡
- Promotes positive mood‡
- Natural precursor to over 150 steroid hormones
- Available in 10 mg and 30 mg capsules
- Made with high-quality vegan ingredients backed by verifiable science
Please see the Supplement Facts tab for a full listing of the Ingredients in this product. In summary, it contains: Pregnenolone (3-beta-hydroxy-5-pregnen-20-one).
Supplement Facts
Suggested Use
As a dietary supplement, take 1 capsule daily, with a meal.
WARNING: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18 YEARS. DO NOT USE IF PREGNANT OR NURSING. Consult a physician or licensed qualified healthcare professional before using this product if you have, or have a family history of, breast cancer, prostate cancer, prostate enlargement, heart disease, low "good" cholesterol (HDL), or if you are using any other dietary supplement, prescription drug or over-the-counter drug. Do not exceed recommended serving. Exceeding recommended serving may cause serious adverse health effects. Possible side effects include acne, hair loss, hair growth on the face (in women), aggressiveness, irritability and increased levels of estrogen. Discontinue use and call a physician or licensed qualified healthcare professional immediately if you experience rapid heartbeat, dizziness, blurred vision or other similar symptoms. KEEP OUT OF REACH OF CHILDREN. To report any adverse event call 1-800-332-1088.
Storage
Store in a cool, dry place.
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4.1 ★★★★★
Based on 28 reviews
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Product Reviews
★★★★★ 5
A little goes a long way
Size: 4 Ounce (Pack of 1), Set name: Adult Mint
A mild tasting toothpaste that is very effective at both gently cleansing and gradually filling in cracks and fractures. I had a chip off of one canine that was actually starting to be painful. I have every motivation not to seek dental treatment because of special needs that require I be under general anesthesia in a hospital operating room as a high risk surgical patient. The last time I had dental work, I sprang a rare reaction, they could not use the one reversal agent every OR has to have on hand for this rare reaction. The board-certified Harvard-trained anesthesiologist had to use other means to bring me through. I no longer can travel the thousands of miles to this one specific hospital that knows my case, which is also why I was looking for some way to fill this chipped tooth on my own. I have been treating this tooth for several months by brushing everywhere but this tooth and holding the paste in the mouth for a time before rinsing out well. I have, concurrently, been using the "Shine" powder, not to clean but as a crevice filler because it strikes me as possibly too abrasive. "Shine," however, is grittier, has some interesting animal-based ingredients, and lacks the glycerin that is present in the Himalayan formula, meaning: adherence ought to be more effective without the oil slick. The non-nano "Shine" seemed to be the most helpful in the beginning of my self treatment. However as I gradually built up a protective initial layer on the tooth, this smoother Himalaya formula with the nano hydroxyapatite worked much better as a "finisher" to consolidate and maintain the tooth coating I had slowly built up. I am not claiming a permanent solution, nor am I claiming that it is possible to achieve what I have without diligence and care and real time. There is no substitute for seeing the dentist if you are in trouble. I am only reporting that this toothpaste works IF you do your twice daily maintenance work and eat carefully around a tooth that is slowly mending. The pain is now gone, the tooth surface is smooth. It feels like any other tooth in my head. Yes, this toothpaste is pricey but a tiny amount on a wetted toothbrush goes a long, long way and generates lots of foam. It does not leave a gummy residue on the rest of one's teeth like the "Shine" powder does. The taste is a mild, very smooth mint, not at all overwhelming. Excellent product.
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Reviewed in the United States on April 23, 2024
★★★★★ 5
TLDR product abides by the SCCS's standards, makes my teeth less sensitive, just too expensive
Size: 3 Ounce (Pack of 1), Set name: Adult Mint Extra Strength, Size: 3 Ounce (Pack of 1), Set name: Adult Mint Extra Strength
This review is very important for me to write, as researching products for health typically stresses me out immensely when there is conflicting information. Nano-hydroxyapatite toothpaste is no exception to this, so if I can save someone some time and stress in this age of overwhelming, conflicting medical information, I will.
I don't use fluoride and was using Tom's toothpaste for a while. My tooth chipped on a mug (second time in my life), and I started stressing about my teeth being "weak." That was when I began researching how to strengthen them, and learned about remineralization and how fluoride helps with that. I learned about Nano-hydroxyapatite (nanoHAP) as an alternative, and essentially that 10% nanohap in the toothpaste was necessary for efficacy. I ordered an affordable (ish) one on Amazon, we'll call it Brand A, and went about my life.
Unfortunately, later on, I learned of concern in the scientific community about nano particles crossing the blood brain barrier, leaking into the bloodstream, and overall just potentially being harmful. I'd already been using the Brand A for 6 months and was afraid of any damage I may have done. I went back to digging.
The FDA has not approved nanoHAP in toothpaste as of now, but I haven't always waited for them to catch up to research to try new things when it comes to my health. In this instance, however, I was definitely looking for someone more knowledgeable than me to guide me, as I was overwhelmed and STRESSED (my health is just one big rollercoaster ride, so I burn out quickly when it comes to health decisions.) Finally, I found that the European Commission's Scientific Committee on Consumer Safety made a decision on the safety of nanoHAP in toothpaste, stating:
"Based on the data provided, the SCCS considers hydroxyapatite (nano) safe when used
at concentrations up to 10% in toothpaste, and up to 0.465% in mouthwash. This safety evaluation only applies to the hydroxyapatite (nano) with the following
characteristics:
- composed of rod-shaped particles of which at least 95.8% (in particle number) have an
aspect ratio less than 3, and the remaining 4.2% have an aspect ratio not exceeding 4.9;
- the particles are not coated or surface modified"
It turns out, Brand A's nanoHAP toothpaste used needle-shaped (not rod-shaped) particles (NOT good.) I was now on a mission to find a safe nanoHAP toothpaste.
In the interim, I switched from the Brand A's nanoHAP toothpaste to Himalaya Botanique's Xylitol toothpaste (no fluoride or nanoHAP.) My teeth and gums became sensitive rather quickly. I was desperate to go back to nanoHAP, but most brands won't disclose the important information in the product pages, or even if you reach out and ask them, i.e. the percentage of nanoHAP (you want 10%), the particle shape (you want rod), etc.
I found Himalaya Botanique's extra strength nanoHAP toothpaste (they have a regular one which doesn't advertise it's % - it's only 2.5%.) I decided to email them and see if they'd answer some questions about the product.
Much to my relief, they responded with this:
"The nano-hydroxyapatite used in Himalaya’s toothpaste complies with the recommendations suggested by the European Union (EU) Scientific Committee on Consumer Safety (SCCS). Please note, this applies to both the shape of the nHA as well as the aspect ratio as recommended by the EU-SCCS.
Himalaya’s hydroxyapatite particles are currently nanoparticles < 100 nanometers (i.e., 0.100 microns), with a nano-rod shape having a width between 5-20 nm (typically close to 10 nm) and a length below 50 nm (typically between 30 to 40 nm)."
That was good enough for me; I bought it. The sensitivity in my teeth from the xylitol toothpaste went away quickly, so it appears to be effective.
It seems to whiten decently, nothing too drastic. I LOVE that the ingredients are all natural, though. It's minty and refreshing. It's not too thick or runny (took a pic trying to show texture and thickness), and my mouth feels clean after brushing.
My only, ONLY complaint is the price. That's why I'm docking a star. $19 for a single tube of toothpaste almost feels like elitism. I'm stretching that tube as FAR as it will go.
I hope this review was helpful. There are lots of studies you can check out regarding nanoHAP, but I hope I summarized the important parts here. Happy brushing!
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Reviewed in the United States on June 26, 2025
★★★★★ 5
Great healthier option
Size: 3 Ounce (Pack of 1), Set name: Adult Mint Extra Strength
⭐️⭐️⭐️⭐️⭐️
Himalaya Botanique Whitening with Extra Strength Hydroxyapatite Toothpaste is outstanding. The nano hydroxyapatite truly makes a difference my teeth feel stronger, smoother, and noticeably cleaner after each use. It helps with remineralization and enamel support without being harsh, and the gentle whitening is a nice bonus. I love that it’s vegan and made with clean ingredients, and the mint flavor is fresh without being overpowering. This feels like a premium, effective toothpaste that delivers real results. I would absolutely repurchase.
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Reviewed in the United States on December 30, 2025
★★★★★ 4
Good! Works pretty well. Has a couple issues
Size: 4 Ounce (Pack of 1), Set name: Adult Mint
I have wanted to dump Fluoride for decades; however, when I stopped it and used all natural products sans fluoride...my teeth became sensitive...so I went back.
Saw this and did slight reading about it. Bought immediately. Ordered a second tube.
LOVE IT. No fluoride. No sensitivity.
Not really sure that it whitens much so I am now shopping for that.
It is pricey, IMHO.
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Reviewed in the United States on August 12, 2025
★★★★★ 5
Minty & Whitening Approved!
Size: 4 Ounce (Pack of 4), Set name: Adult Mint
MY FAVORITE fluoride free toothpaste. I still get that slight minty fresh taste and has effectively whitened my teeth as people have noticed and complimented me on.
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Reviewed in the United States on May 1, 2026