SKU: 41046480986

Berberine Pro - 600 mg, 60 capsules

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Description

Berberine Pro - 600 mg, 60 capsulesDiscover the Power of BerberineAdvanced Metabolic Support for Healthy Aging. Helps maintain healthy blood sugar levels*1 6 Supports cardiovascular health and lipid metabolism*1 6 Supports a balanced gut microbiome*3,5,7 Activates AMPK, the "longevity switch" of cellular energy and metabolism* 1 2 View Certificate of Analysis Berberine is a powerful metabolic optimizer that enhances the bodys ability to process carbohydrates and fats. It promotes the

Discover the Power of Berberine—Advanced Metabolic Support for Healthy Aging.

  • Helps maintain healthy blood sugar levels*1-6
  • Supports cardiovascular health and lipid metabolism*1-6
  • Supports a balanced gut microbiome*3,5,7
  • Activates AMPK, the "longevity switch" of cellular energy and metabolism* 1-2

View Certificate of Analysis

Berberine is a powerful metabolic optimizer that enhances the body’s ability to process carbohydrates and fats. It promotes the conversion of food into energy, supports nutrient storage and distribution, and aids systems that manage energy balance. By optimizing these key metabolic processes, berberine helps the body utilize nutrients more effectively.*

What Makes Ours Better?

  • Ultra-Pure Extract: Sourced from the bark of Indian barberry (Berberis aristata), ensuring both exceptional purity and potency, backed by centuries of traditional use.* 
  • Clinical Strength: Each capsule delivers a precise 600mg dose, optimized for maximum efficacy.*
  • Targeted Support: Formulated with alpha-lipoic acid (ALA) to enhance antioxidant protection and support cellular energy.*
  • Enhanced Absorption: Features BioPerine® black pepper extract to boost nutrient absorption and bioavailability.*8

Why Choose ProHealth?

  • Doctor-Formulated: Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*
  • Triple Lab Tested: Rigorously tested three times by independent third-party labs to guarantee unmatched potency and purity.
  • Full Transparency: In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle.
  • Manufactured in the USA: Since 1988, we’ve proudly produced our supplements in FDA-regulated, GMP-certified facilities, ensuring the highest quality and safety standards.
  • 100-Day Risk-Free Guarantee: We stand behind our products. If you’re not completely satisfied, contact our Santa Barbara, CA office for a full refund—no hassle, no questions asked.*8

Advanced Metabolic Support for Healthy Aging
Berberine is a bioactive plant extract with a rich history of use in Ayurvedic and Chinese medicine. As a “pleiotropic” compound, it delivers a wide range of benefits and influences multiple systems in the body. While berberine is best known for supporting healthy blood sugar levels, it also plays a key role in various biochemical pathways associated with healthy aging and longevity.*1-7,9-10

Helps maintain healthy blood sugar levels*
Berberine is widely recognized for its role in glucose support, working through multiple pathways at once. It influences glucose absorption in the intestines, supports glucose uptake in the liver and muscles, interacts with gut microbiota, influences glucose production, and helps the body use energy efficiently. The net effect is that berberine helps maintain blood sugar levels already within the normal range.*1-6

Supports cardiovascular health and lipid metabolism*
Berberine helps maintain healthy cholesterol levels and supports blood vessels by protecting the cardiovascular system from age-related oxidative stress and inflammation. Research suggests it supports healthy blood pressure levels already within the normal range, partly by influencing nitric oxide production and helping defend against free radical damage that contributes to cardiovascular aging.*1-6

Supports a balanced gut microbiome*
Although berberine has low bioavailability when taken orally, research has begun to explore its benefits inside the gut. Berberine appears to act as a prebiotic-like compound, supporting beneficial gut bacteria and promoting microbial diversity. Studies suggest it influences Akkermansia muciniphila, a bacterium associated with gut barrier integrity, immune function, and metabolic health. Additionally, berberine has been shown to boost gut mucin secretion, which helps maintain a balanced microbiome and supports overall digestive and metabolic health.*3,5,7

Activates AMPK, the "longevity switch"*
Berberine is known to boost AMP-activated protein kinase (AMPK), which is an energy sensor that regulates metabolic changes. AMPK, which is vital for mitochondrial production, metabolic function, and cellular cleanup (autophagy). By influencing this key pathway, berberine helps optimize energy production, enhance metabolic health, and promote cellular repair, supporting the maintenance of healthy cells, DNA, and mitochondria. These effects make berberine a powerful natural compound for promoting longevity, health span, and vitality.*1,2

Beyond activating the AMPK pathway, berberine has been shown to rejuvenate aging senescent cells in recent research by influencing other key longevity pathways, including PCG1-α, SIRT-1, and mTOR.*3

Discover the power of Berberine—ProHealth’s trusted formula for advanced metabolic support and healthy aging, featuring TikTok’s trending botanical.

Ingredients:

  • Chromium: A trace mineral involved in carbohydrate metabolism and glucose utilization.*
  • Berberine: A yellow plant alkaloid that supports healthy blood sugar levels, metabolic function, and longevity by activating AMPK.*
  • BioPerine® Black Pepper: A patented extract that boosts the absorption and bioavailability of key ingredients.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

References:

  1. Stancu AL. AMPK activation can delay aging. Discoveries (Craiova). 2015;3(4):e53. Published 2015 Dec 31. doi:10.15190/d.2015.45
  2. Koppen LM, Whitaker A, Rosene A, Beckett RD. Efficacy of Berberine Alone and in Combination for the Treatment of Hyperlipidemia: A Systematic Review. J Evid Based Complementary Altern Med. 2017;22(4):956-968. doi:10.1177/2156587216687695
  3. Yin J, Xing H, Ye J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism. 2008;57(5):712-717. doi:10.1016/j.metabol.2008.01.013
  4. Baziar N, Nasli-Esfahani E, Djafarian K, et al. The Beneficial Effects of Alpha Lipoic Acid Supplementation on Lp-PLA2 Mass and Its Distribution between HDL and apoB-Containing Lipoproteins in Type 2 Diabetic Patients: A Randomized, Double-Blind, Placebo-Controlled Trial. Oxid Med Cell Longev. 2020;2020:5850865. Published 2020 Mar 9. doi:10.1155/2020/5850865
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
Chromium
 (as Chromium Picolinate)
200 mcg 571%
Berberine HCl (from Berberis
  aristata Bark Extract)
600 mg
BioPerine® Black Pepper Fruit
  Extract (95% Piperine)
3.4 mg
† Daily Value (DV) not established

Rev. 09.25

BioPerine® is a registered trademark of Sabinsa, Co.

  • OTHER INGREDIENTS: Hypromellose (capsule), rice flour.
  • SUGGESTED DAILY USE: Take one (1) capsule 2-3 times per day with food.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.
  • NOTE: Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. KEEP OUT OF REACH OF CHILDREN
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 41046480986

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Mary Roberts
Waukegan, US
★★★★★ 2
It doesn’t do what is supposed to do
Color: Blue
Wasn’t impressed..,all the ball does is vibrate. It doesn’t really bounce
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 6, 2026
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Brittany Manos
Lake Worth, US
★★★★★ 5
My dogs fight over it
Color: Orange, Color: Orange
Easy to use, durable, and has a great battery love. At first my dogs were curious and unsure about it, now its become one of their favorite toys. They'll stare at it while its being charged and impatiently wait for it so they can have fun again. Perfect size for most breeds.
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Reviewed in the United States on January 3, 2026
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brownie2009
Waukegan, US
★★★★★ 5
Great dog birthday gift
Love it. Is it the best ball ever? No. I love it because my dog can find it if he lost track of it while I was poorly throwing the ball. Also, if it starta getting dark out and he has it in his mouth, I know exactly where he is. The glow is great! Pretty bright, changes colors, activatws after a hard bounce. Changing the battery is easy and just takes a screwdriver. Bounce is pretty good. Dog really likes it. He likes things that glow. It has held up so far, and one of the other dogs, who likes to destroy things, got ahold of it. He is working on not wrecking things, but I know he tried for a little bit and there has been no damage. The ball does have quite a bit of heft to it, so a small-ish dog isn't going to like the size or weight, likely.
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Reviewed in the United States on April 21, 2026
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Leo
Houston, US
★★★★★ 5
Freaking works great !
Met and exceeded my expectations! It's very durable , it has become my dogs favorite ball, it is easily seen in the snow, and at night!!
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Reviewed in the United States on January 6, 2026
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P. Williams
Chelsea, US
★★★★★ 5
A bit pricey, but then again, our new inflated economy
Nite Ize makes great products. I especially like the extended time the ball stays lit. Especially for those times the dog decides not to retrieve and you're searching the ground for the ball in the dark. It's heavy. Good for power chewers. Not a lot of bounce but then again the light function is the primary goal.
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Reviewed in the United States on December 31, 2025

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