SKU: 16578426619

Zoetis INFORCE 3® Respiratory Vaccine

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Description

Zoetis INFORCE 3® Respiratory VaccineRespiratory disease can challenge young calves and dairy cows immediately before and at calving. INFORCE 3 the market leading cattle respiratory vaccine1, is for the vaccination of healthy cattle, including pregnant cows, to help protect against respiratory disease caused by bovine respiratory syncytial virus (BRSV), infectious bovine rhinotracheitis (IBR) virus and parainfluenza3 (PI3) virus. For dairy herds, INFORCE 3 can be used in calves as young

Respiratory disease can challenge young calves and dairy cows immediately before and at calving. INFORCE 3® the market-leading cattle respiratory vaccine1, is for the vaccination of healthy cattle, including pregnant cows, to help protect against respiratory disease caused by bovine respiratory syncytial virus (BRSV), infectious bovine rhinotracheitis (IBR) virus and parainfluenza3 (PI3) virus. For dairy herds, INFORCE 3 can be used in calves as young as 3 days old, at weaning, before moving to group pens, or with cows and heifers at prefreshening.

Indications
Helps protect against respiratory disease caused by BRSV, IBR and PI3.
Available As

Vials

For use with

Beef

Dairy

How it Works

As an intranasal respiratory vaccine, INFORCE 3® causes a local immune response with viral antibodies produced in the nasal passage where BRSV, IBR and PI3 are most likely to enter the animal’s system.

INFORCE 3® is the first commercially-available intranasal respiratory vaccine to help protect against respiratory disease caused by BRSV, while also protecting against IBR and PI3, to help get cattle off to a healthier, more productive start.

INFORCE 3 has a six-month duration of immunity claim for IBR protection, and a single-nostril administration claim. Additional research also demonstrated no maternal antibody interference for IBR and BRSV.2,3

Safe for all ages, types and classes of cattle

INFORCE 3® is safe for use in all types, ages and classes of cattle. INFORCE 3 was demonstrated safe for use in very young, high-stress calves; weaned and high-stress stocker calves; and pregnant heifers and cows.

The Science Behind Effective Control

  • Intranasal administration works with the animal's immune system for fast, effective response
  • Helps prime the immune system for a memory response to subsequent vaccinations as well as disease challenges
  • Contains proprietary, temperature-sensitive IBR and PI3 strains that replicate most effectively in the upper respiratory tract
  • Stimulates interferon release for protection
  • Helps deliver a healthy start for young dairy calves

Proven Respiratory Disease Protection

  • In two different studies, all calves vaccinated with INFORCE 3 survived severe BRSV challenges in which 100% and 90% of unvaccinated controls either died or had to be humanely euthanized.4,5
  • INFORCE 3 was shown to help prevent respiratory disease caused by IBR and PI3 and reduce level and duration of viral shedding caused by IBR and PI3.6-8
  • A study comparing INFORCE 3 and TSV-2® demonstrated that vaccinating cows and heifers with INFORCE 3  prior to freshening helped support overall positive production:
    • 205 pounds more milk per cow per lactation9
    • Increased income per cow9

Directions

Aseptically rehydrate the freeze-dried vaccine with the sterile diluent provided, mix well and administer 2 mL intranasally using a cannula. Place the 2-mL dose in a single nostril or place 1-mL in each nostril. 

Calves vaccinated before the age of 6 months should be revaccinated after 6 months of age to avoid possible maternal antibody interference with immunization. Annual revaccination with a single dose is recommended. 

For further advice on revaccination frequency, consult your veterinarian.

PRECAUTIONS:

  1. Store at 2°-8°C. Prolonged exposure to higher temperatures and/or direct sunlight may adversely affect potency. Do not freeze.

  2. Use entire contents when first opened.

  3. Sterilized syringes should be used to administer this vaccine. Do not sterilize with chemicals because traces of disinfectant may inactivate the vaccine.

  4. Inactivate unused contents before disposal.

  5. Do not vaccinate within 21 days before slaughter.

  6. Contains gentamicin as preservative.

  7. Fetal health risks associated with the vaccination of pregnant animals with modified live vaccines cannot be unequivocally determined during clinical trials conducted for licensure. Appropriate strategies to address the risks associated with modified live vaccine use in pregnant animals should be discussed with a veterinarian.

  8. As with many vaccines, anaphylaxis may occur after use. Initial antidote of epinephrine is recommended and should be followed with appropriate supportive therapy.

References

  1. Based on number of doses and overall sales of respiratory vaccines. Animalytics Segment Data, Biologicals Therapeutic Category, Ending MAT May 2021.
  2. Mahan SM, Sobecki B, Johnson J, et al. Efficacy of Intranasal Vaccination With a Multivalent Vaccine Containing Temperature-Sensitive Modified-Live Bovine Herpesvirus Type 1 for Protection of Seronegative and Seropositive Calves Against Respiratory Disease. J Am Vet Med Assoc. 2016;248(11):1280-1286.
  3. Ellis JA, Gow SP, Mahan S, Leyh R. Duration of Immunity to Experimental Infection With Bovine Respiratory Syncytial Virus Following Intranasal Vaccination of Young Passively Immune Calves. J Am Vet Med Assoc. 2013;243(11):1602-1608.
  4. Data on file, Study Report No. 3131R-60-08-557, Zoetis Inc.
  5. Data on file, Study Report No. 3131R-60-09-669, Zoetis Inc.
  6. Data on file, Study Report No. 3131R-60-08-548, Zoetis Inc.
  7. Data on file, Study Report No. 3131R-60-09-720, Zoetis Inc.
  8. Data on file, Study Report No. 3131R-60-08-568, Zoetis Inc.
  9. Data on file, Study Report No. 10PETINF01, Zoetis Inc.
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Exchange/Return Notes
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SKU: 16578426619

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Daniel F.
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★★★★★ 4
Overall great
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Reviewed in the United States on May 29, 2020
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Arandombuyer
Houston, US
★★★★★ 5
Great, but add a little space
Color: Black, Size: Compact, Color: Black, Size: Compact
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Reviewed in the United States on May 16, 2026
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Robert
Louisville, US
★★★★★ 5
So Comfy!
So soft, so comfy! I have never had a wrist rest before, but since upgrading to my first custom keyboard, which is higher off of the desk than my previous one, I wanted some comfort and support. This wrist rest is perfect, but keeping in mind it is meant for ten keyless keyboards, and my keyboard is also made by Glorious, it is perfect size and height. For a slimmer lower profile keyboard it might be a bit tall. I would make sure that your keyboard thickness will accommodate how thick this thing is. It is nice and firm, and should hold up for a long time :)
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Reviewed in the United States on July 17, 2025
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Mike B.
Dallas, US
★★★★★ 5
Great for the Logitech G915 and G915X
Color: Stealth, Size: Full Size
Pretty much the perfect size and height for comfortable, ergonomically-correct typing on the low-height gaming keyboards like the G915 and G915X from Logitech. Got one of these for work and loved it enough to get one for home as well.
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Reviewed in the United States on April 12, 2026
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Amazon Customer
Fort Morgan, US
★★★★★ 5
so I felt like it was time to invest in a wrist pad
Color: Black, Size: Full Size
Im an Editor and spend most of my days typing in front of a computer. I've never really used a wrist pad before, but my wrists were laying on the edge of my desk, which after a while, began to hurt my wrists, so I felt like it was time to invest in a wrist pad. I looked at plenty of them here on Amazon and this one from Glorious had some great reviews, so I thought I'd give it a try. Even though I'm not a "gammer," this rest is beyond awesome! It's perfect for typing all day, and even though some reviews noted that it was too "high" - it's really not and works great on a keyboard with a kickstand under it, or even when I'm not using my wireless keyboard, it still works great typing on my MacBook Air (2015 Edition). It has a sticky underside that keeps it in place, but it's also not too sticky, so you can move it around with ease. I will admit, it is a little firm, so if you're looking for a wrist pad that's "gel-like" for your wrists to sink into - this is not for you. It's firm and holds your wrists up above the keyboard so that you're typing downward, rather than having your wrist slanted up at a 45 degree angle, which is terrible for you. I've only had the wrist pad for 2 days, but I can't tell you how much pain it's relieved from my wrists sitting on the edge of my desk. The full length one fits perfectly with my keyboard with the numbers extended on the right side, and should I decide to only use my laptop's keyboard, the pad works great for that as well. Would highly recommend to anyone who is looking for a solid, firm pad to rest your wrists on while typing.
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Reviewed in the United States on January 15, 2016

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