SKU: 10155088972

B12-ND

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Description

B12-NDShould you consider vitamin B12 as part of your dietary supplement regimen? For most people, it may be difficult to get a sufficient amount of vitamin B12 from their diet because the sources of vitamin B12 are mostly found in high calorie foods (such as cheese and milk) which can lead to overweight and other health compromises. A lesser known natural source high in B12 is sprouts, but more difficult to obtain or eat in large amounts. B12 as

Should you consider vitamin B12 as part of your dietary supplement regimen?  
For most people, it may be difficult to get a sufficient amount of vitamin B12 from their diet because the sources of vitamin B12 are mostly found in high calorie foods (such as cheese and milk) which can lead to overweight and other health compromises.  A lesser known natural source high in B12 is sprouts, but more difficult to obtain or eat in large amounts.

B12 as Methylcobalamin, Adenosylcobalamin and Hydroxycobalamin
Premier Research Labs’ B12-ND contains fully active co-enzymes of vitamin B12 that are rich in the desirable “blood circulating forms” of vitamin B-12 , namely, methylcobalamin, adenosylcobalamin and hydroxycobalamin. While the body is able to absorb food-source vitamin B12, it must further convert it to these three coenzyme forms in order for it to become metabolically active. When vitamin B12 is provided as methylcobalamin, it is already in the biologically active form and is able to yield optimal bioavailability and tissue retention. B12-ND is a probiotic-fermented, vitamin B12 formula that uses a unique probiotic culture which allows rapid oral delivery with superior bioenergetic properties. Our probiotic fermentation is cultured without the use of animal sources, making it suitable for vegetarians and vegans.

Brain and Nerve Health
The fully active co-enzymes of vitamin B12, specifically methylcobalamin, may support healthy brain cell activity including memory, mood and cognitive health.  In addition, methylcobalamin promotes neurological functions by encouraging protein synthesis to sustain healthy nerve cells. 

Energy Metabolism and Blood Health
It is the coenzyme of vitamin B12, methylcobalamin, that synergizes with other B vitamins to support DNA and red blood cell health.  Through a series of biochemical reactions with homocysteine, these coenzyme factors of vitamin B12 are not only important to energy metabolism but critical to the methionine synthase pathway, supporting healthy homocysteine metabolism and S-adenosylmethionine (SAMe) production.  Methylcobalamin, the coenzyme form of vitamin B12, is the preferred form of B12 that is necessary for homocysteine modulation and the formation of methyl donors involved in cardiovascular function, sleep, blood cell formation, and nerve function. 

Probiotic-Cultured Delivery System
B-12ND is a revolutionary, highly absorbable delivery system made with our signature probiotic-cultured technology. Through a micro-cultured delivery system, it is the first B12 nutraceutical preparation designed to assure rapid absorption of these blood circulating forms of B-12. Even those with poor digestion can enjoy the full benefits of b 12’s highly bio-available co-enzyme B-12 liquid nutrients. No other form of B-12 can offer this type of bioavailability and quality.

Support energy, memory, mood, cognitive health, homocysteine modulation, neurological function and whatever else life throws your way! Premier Research Labs B-12 ND delivers unmatched results for when you need it most.  Nothing works like B-12 ND!

Suggested Use

Take 1/4 teaspoon mixed in 4 oz. of water daily. Shake gently before use. Refrigerate after opening.

Ingredients
Serving Size 1/4 Teaspoon (1.25 mL)
Vitamin B12 
(as methylcobalamin, adenosylocobalamin, hydroxcobalamin); Fermented in a probiotic culture1
1000mcg
Other Ingredients: Purified Water, Organic Cane (Grain-Free) Alcohol, Organic Molasses, Organic Cane Sugar


1Probiotic culture inactivated after fermentation; preserved with organic alcohol

 

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SKU: 10155088972

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4.8 ★★★★★
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Verified Purchase
James C Stringham
West Palm Beach, US
★★★★★ 5
Best dog snack around.
These are my dog’s favorite snacks in the world. They are fresh, healthy, and the dog thinks she’s getting a naughty snack because they’re sweet! 😆
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 6, 2026
D
Verified Purchase
Dian B.
Cuba, US
★★★★★ 5
Good treats
Dogs love these! We have Chihuahuas and have to cut these in half for them as a while one is too large.
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Reviewed in the United States on May 30, 2026
K
Verified Purchase
Kiki
Massapequa, US
★★★★★ 5
Healthy, Slightly Soft/Chewy Treat!
VERY pleased to have found these! Wanted something to offer Mookie as a "special treat" (a step up from Milkbones, but NOT long-lasting) that was healthy and easily digestible. He wasn't sure what to make of them at first... they're fairly soft and a little chewy, and they just smell like FRESH sweet potatoes -- not any fake meat or seasoning. Once he started chewing, however, he got very excited about the new treat, and now when he hears the bag being handled/opened, he comes running and does his little happy dance! We'll be keeping these on hand because the quality and reasonable price - combined with the LACK of tummy distress and his enjoyment - make this a "go-to" special reward.
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Reviewed in the United States on January 4, 2026
D
Verified Purchase
Dawn
Bozeman, US
★★★★★ 5
A Nutritional Treat!
My German Shepherd loves this so much, I sometimes use it as a training treat! Sweet Potato is beneficial to dogs. The only complaint I have is the size consistency from bag to bag.
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Reviewed in the United States on May 8, 2026
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Verified Purchase
Sandy H
Fort Morgan, US
★★★★★ 4
They used to be soft and moist but not now
These used to be one of my dogs’ favorite sweet potato treats, but they’ve gotten too hard and thick to cut for their morning snack or cut for their puzzle pieces. Because they’re not only too hard to cut, they’re also too hard for them to eat. Both, my Maltese and Shih Tzu love sweet potato treats, but they leave the dry ones behind. Since something made the Shih Tzu so sick that I had to spend a small fortune at the vet trying to make her better, she avoids all dry treats now and unfortunately that includes a lot of necessary nutrients. I hope these go back to being soft and moist the way they used to be!
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Reviewed in the United States on March 25, 2026

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