SKU: 8668736700

SR-9011 Powder, 1gr

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Description

SR-9011 Powder, 1grSR 9011 SR 9011 is a research drug developed by Professor Thomas Burris at the Scripps Research Institute. It acts as an agonist for Rev ErbA with a half maximal inhibitory concentration (IC50) of 790 nM for Rev Erb and an IC50 of 560 nM for Rev ErbA. This drug is primarily used in studies exploring the regulation of circadian rhythms and its potential implications for the immune system, inflammation, and cancer. SR 9011 belongs to the second

SR-9011

SR-9011 is a research drug developed by Professor Thomas Burris at the Scripps Research Institute. It acts as an agonist for Rev-ErbAα with a half-maximal inhibitory concentration (IC50) of 790 nM for Rev-Erbα and an IC50 of 560 nM for Rev-ErbAβ. This drug is primarily used in studies exploring the regulation of circadian rhythms and its potential implications for the immune system, inflammation, and cancer.

SR-9011 belongs to the second generation of Rev-ErbA activators and is found in high concentrations in various tissues such as the liver, skeletal muscles, adipose tissue, and the brain.

For more information, see the study on  SR-9009 and SR-9011


half-life
4 hours.

DISCLAIMER
This material is sold for use in laboratory research only. Terms of sale apply. Not for human consumption, nor for medical, veterinary or domestic use. Please familiarize yourself with our DISCLAIMER before ordering.

Included is a precision pipette marked per 0.2 ml!
Shake well before use.

Data sheet

SR9011 – Solution, 600mg (20mg/mL)

Application Rev-ErbA Agonist
CAS 1379686-29-9
Molar Mass 479.04 g/mol
Chemical Formula C23H31ClN4O3S
IUPAC Name 3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide
Synonyms SR9011, 1379686-29-9, SR-9011, CHEMBL1961797, GTPL8900, MolPort-044-561-120, PPUYOYQTTWJTIU-UHFFFAOYSA-N, KS-00000TT2, BDBM50366239, AKOS030526466, CS-4668, SR 9011, NCGC00347956-01, AK547296, HY-16988, 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-, 3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide
Storage Store at room temperature, tightly sealed, away from heat, light and moisture.
Solubility
Organoleptic Profile
Physical Form Powder
Specification
Terms This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.
Shipping Notes
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Exchange/Return Notes
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SKU: 8668736700

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4.7 ★★★★★
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C
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C J M
Omaha, US
★★★★★ 5
I can Sleep Again!
I can get terrible dry mouth while sleeping. These have made it so I can sleep the whole night with out waking up to drink water. I love theses. Gave me back a good nights sleep. I use Two every night. Simple get it a little wet, then I place gently and hold to the outside of the top left molar for a few seconds. The glue will hold it in place with out fear of swallowing. Then I put one on the top right side. They stick well to teeth and can be easily removed. If you leave it alone and fall asleep, it will stay in place for 4-6 hours, providing gentle lubrication to keep your mouth moistened while sleeping. They make your mouth water a little, and the xylitol gives a little lubrication. These are great for mouth breathers and people with sinus issues. These are a real game changer for the better.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 25, 2019
D
Verified Purchase
D. Hooper
Lowell, US
★★★★★ 4
Xylimelts
Have been using for years. So glad they have these without the mint. Just wish they lasted longer at night but they do the job. Taste is pleasant and they are easy to use.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 16, 2025
N
Verified Purchase
N. A. Wysock
West Palm Beach, US
★★★★★ 5
Dry Mouth Relief
Having been using these for quite awhile now for a severe dry mouth. They really help to make the mouth create saliva, thus protecting the teeth from erosion, etc. They are discs with a dark side which is placed above the teeth on the gum. It will stick there in a minute or two and remains in place until it melts and disappears. I use two at night and have never had a problem with them coming loose, this creating a choking hazard. They remain i place and melt. Sometimes I wake at night and my mouth is dry, so put a couple more in and I'm good to go until morning. I would recommend these to anyone with a dry mouth. There is no bad taste. They are somewhat expensive when using long term, but worth it to me. Have not found them locally, although Walmart has them online...same price or a little more than Amazon. Will continue to buy from these sellers.
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Reviewed in the United States on June 21, 2017
P
Verified Purchase
Peter Pumpkin Eater
Birmingham, US
★★★★★ 5
If you have dry mouth, these are a fantastic option!!
I am a pharmacist, so I have come across and used a lot of different products to try to treat the chronic dry mouth problem that I have. This is by far the BEST product I have come across. They are a bit expensive, but I consider them worth the cost. You place the disc in your mouth, on your gum, and it adheres to the gum. The product lasts for a good hour for me. I use them when I go to sleep, to help avoid dry mouth and drainage down my throat when going to sleep. I use 2 when I go to bed, and sometimes have to wake up in the middle of the night to use 2 more. But I love them!! A similar product is OraMoist, but that product turns to a gel-like goo that I found very distasteful. Biotene is highly advertised, but absolutely useless for my problem. It made my throat scratchy and made me cough. Use this product instead!!
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Reviewed in the United States on June 18, 2019
J
Verified Purchase
J. Goodwin
Fort Morgan, US
★★★★★ 5
Always keep them at hand
After radiation I was left with compromised saliva production and these Xylimelts really help. I use one any time I feel my mouth becoming dry, when I’m going to do any sort of physical activity, when the weather is hot, after eating astringent foods or drinks - because the taste is very mild you can even keep one in your mouth while eating or drinking. They agreed really, really well out of sight on my gum line. I always put one in at night before sleep as I’m pretty sure they cut down on the dry throat that can lead to snoring. I have a pack in each purse, glove compartment, gym bag and pre-load several packs in my luggage so they’re always available. One of those little things that makes life easier and more pleasant. I’m overjoyed I survived cancer, but there have been changes after the fact. Xylimelts make at least one a whole lot easier to bear
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 14, 2020

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