SKU: 55951036680

SkinCeuticals® Silymarin CF

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Description

SkinCeuticals® Silymarin CFSilymarin CF is our vitamin c antioxidant serum formulated for oily and acne prone skin types to reduce oiliness, refine texture and enhance skin clarity for healthier looking results. With a powerful antioxidant combination, this l ascorbic acid serum blends vitamin c, ferulic acid, silymarin and salicylic acid for the ideal oil free solution for blemish prone skin. Provide skin with effective antioxidant protection against free radical damage to

Silymarin CF is our vitamin c antioxidant serum formulated for oily and acne-prone skin types to reduce oiliness, refine texture and enhance skin clarity for healthier-looking results. With a powerful antioxidant combination, this l-ascorbic acid serum blends vitamin c, ferulic acid, silymarin and salicylic acid for the ideal oil-free solution for blemish-prone skin. Provide skin with effective antioxidant protection against free radical damage to minimise the formation of fine lines, wrinkles and unrefined skin texture.

Visible Results

The measure of an antioxidant is not only its environmental protection, but its visible results. Silymarin CF clinical studies show a reduction in oiliness, refined skin texture, and an improvement in skin clarity, fine lines, and overall appearance.

Reduces oil oxidation by up to 76% (Statistically significant change from baseline (p <0.001). Protocol: Sebum collected from the forehead of 35 subjects in China with oily skin, after 4 weeks of Silymarin CF use. The ratio of squalene to squalene peroxides was measured).

After 1 week, a 16% reduction in oiliness (Statistically significant change from baseline (p≤0.05). Protocol: A 12-week, single-center clinical studies conducted on 60 men and women ages 18-50 with oily and blemish-prone skin. Silymarin CF was applied once daily in conjunction with a sunscreen. (Brazil, 2020)).

At 4-weeks 12% improvement in overall appearance, 13% improvement in clarity, and 13% improvement in Post-Inflammatory Hyperpigmentation. After 8 weeks, a 25% improvement in clarity, 38% improvement in texture, 24% improvement in fine lines, 38% improvement in radiance, 28% improvement in skin tone evenness, 41% improvement in overall appearance (Statistically significant change from baseline (p≤0.05). Protocol: an 8-week, single-center clinical study conducted in the USA on 55 women ages 25–50 with mild to moderate signs of photodamage. Silymarin CF was applied once daily in conjunction with a sunscreen).

How To Use

Gently press 4-5 drops of the vitamin c serum onto skin after cleanser and toner, focusing on the facial canvas, neck and chest before completing your skincare routine for oily skin.

Pair this antioxidant serum with a broad-spectrum sunscreen such as the SkinCeuticals Ultra Facial Defense SPF 50+ to maximise your skin's protection against the effects of oxidative damage.

Ingredients

  • L-Ascorbic Acid L-ascorbic acid is a potent form of Vitamin C that provides skin with effective protection against free radical damage, in addition to minimising the signs of visible ageing. This l-ascorbic acid serum contains 15% of the powerful antioxidant ingredient to refine skin texture, enhance skin radiance and reduce oxidative damage.
  • Silymarin Silymarin is an antioxidant derivative of milk thistle, ideal for oily and acne-prone skin types as it works to prevent oil oxidation and is non-comedogenic so prevents the formation of clogged pores. The Silymarin CF Antioxidant Serum contains 0.5% silymarin, boosting antioxidant benefits for protection against free radicals.
  • Ferulic Acid Ferulic acid enhances the effects of other antioxidants such as Vitamin C, to neutralise free radicals and provide preventative protection against visible signs of ageing such as fine lines, wrinkles and dark spots. This antioxidant serum is formulated with 0.5% ferulic acid to protect skin from external aggressors such as UV radiation.
  • Salicylic Acid Salicylic acid is a BHA that offers skin a chemical exfoliation to refine pores and prevent the formation of blemishes, making the ideal ingredient for oily and acne-prone skin. The Silymarin CF vitamin c serum is formulated with 0.5% salicylic acid for effective oil-control and decongestion.

855290 57 – AQUA/WATER, ALCOHOL DENAT., ASCORBIC ACID, PROPYLENE GLYCOL, DIPROPYLENE GLYCOL, LAURETH-23, SILYBUM MARIANUM FRUIT EXTRACT, SODIUM CITRATE, SALICYLIC ACID, FERULIC ACID, D251111/1.

Please be aware that ingredient lists for the products of our brand are updated regularly. Please refer to the ingredient list on your product package for the most up to date list of ingredients to ensure it is suitable to your personal use.

Science & Proof

Growing research shows a link between oil oxidation and the formation of blemishes. When skin’s oils oxidize, this specific type of free radical damage can cause a cycle of inflammation and bacteria that is linked to blemish formation. Daily environmental aggressors like sun and pollution can generate free radicals that further oxidize skin oils. Silymarin CF is scientifically demonstrated to reduce oil oxidation by up to 76%. This combination antioxidant serum is formulated under the Duke Antioxidant patent.

Vitamin C is a highly-potent antioxidant that by its structure has difficultly being effectively absorbed by skin. The Duke Antioxidant patent outlines the formulation parameters required for effective delivery of vitamin C to skin: 1) pure l-ascorbic acid (vitamin C); 2) an acidic pH within the 2.0-3.5 pH range and; 3) a concentration between 10%-20%. SkinCeuticals is the only brand to formulate antioxidants according to these parameters.

Intensive exposure - 68% protection from Erythema at 3x MED (One exposure of x3 minimum erythema doses represents a more intensive exposure one would receive on a sunny day at the beach). Daily exposure - 79% protection from erythema at 1x MED (three consecutive daily exposures of one mimum erythema dose represents chronic inflammation from UV exposure one would encounter in daily life) (Protocol: 10 subjects received application of Silymarin CF on the back for four consecutive days followed by UV-irradiation with one exposure of 3x MED or three consecutive daily exposures of 1x MED. Measurements of erythema and photography were taken 24 hours after the final exposure.)

Shipping Notes
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  • Delivery to the USA:
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 55951036680

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4.0 ★★★★★
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Amy Marie Anderson
Louisville, US
★★★★★ 5
Absolutely amazing masks!!!
Scent: Collagen, Size: 4 Count (Pack of 1)
These masks are beyond amazing! I use one once a week and leave it on overnight after completing my p.m. skincare routine and wake up to smooth, plump, moisturized, and absolutely glowing!! I have extremely sensitive skin and eyes and these masks do not bother me at all. No burning in my eyes and no irritation of the skin. My deep wrinkles seem a lot less pronounced and some of my more fine lines almost disappear for 24 hours after using this mask. They are simple to use and adhere to the skin perfectly even after applying serums and moisturizers. Once the mask is completely absorbed and becomes clear it peels of the skin with ease. Based on the quality of these masks I am shocked by the low price, it is such a great value for your money. This Mask has become a staple in my skincare routine and I will continue to purchase these!!
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Reviewed in the United States on May 10, 2026
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Verified Purchase
Tara Rekatsinas
Massapequa, US
★★★★★ 5
instantly more hydrated + glowy skin
Scent: Collagen, Size: 4 Count (Pack of 1), Scent: Collagen, Size: 4 Count (Pack of 1)
I love this mask. It’s one of those products you can actually see a difference with right after using it. It really helps with: 1. Deep hydration – my skin feels plump and moisturized, not dry or tight 2. Smoother texture – it softens everything and makes my skin feel really smooth 3. Glow/brightness – gives that fresh, healthy glow without looking greasy How I use it: I apply it on clean skin (usually at night), leave it on as directed, and let it fully absorb before removing. I like using it when my skin feels dull or dry and want a quick reset. Overall, it’s super easy to use and makes my skin look more refreshed every time. Definitely a go-to for me.
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Reviewed in the United States on April 28, 2026
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Verified Purchase
Ashley
Battle Creek, US
★★★★★ 4
Woke Up Glowing ✨ (But Sleeping In It Is a Stretch lol)
Scent: Collagen, Size: 4 Count (Pack of 1)
I was honestly impressed with this mask! It feels super soft, cooling, and refreshing while wearing it. The jelly texture makes it feel really hydrating and luxe, like a mini spa night at home. My skin looked smooth, plump, and GLOWING the entire next day after I took it off. Like… noticeably radiant. I also have sensitive skin, so I was a little nervous trying it at first, but I didn’t have any irritation or reaction at all. My skin felt calm, hydrated, and refreshed afterward. One thing I actually liked was that the mask was easy to customize a little. I have a nose piercing, so I just tore a small piece near my nose so it would fit comfortably without irritating it. The material held up perfectly, so that was a nice bonus for anyone with piercings or who just needs a better fit in certain areas. My only complaint is the “sleep in it” part of the instructions. I personally don’t see how that’s possible 😅 The mask stays pretty moist and jelly-like the whole time, so it felt uncomfortable to lay down in and I kept feeling like it would slide around. I ended up just wearing it for a while before bed instead. Overall though, the results were worth it and I’d definitely use it again for the glow alone!
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Reviewed in the United States on May 3, 2026
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Anna
Alexandria, US
★★★★★ 5
Nice mask! Caviar
Scent: PDRN, Size: 4 Count (Pack of 1), Scent: PDRN, Size: 4 Count (Pack of 1)
The first 3 pictures were taken after the first hour and a half. The second 3 pictures were taken at 2 hours. The mask had a hard time dissolving underneath my eyes and around my chin area mostly but everywhere else it hardened within the first hour or so. I will try to wear it for longer than 2 hours next time. To see if that changes, but my skin feels really nice right now. It's a little sticky, but it looks healthy and has a nice glow. Application is easy. I love that its separated into 2 parts. Doesn't fit well around the nose between the eyes and doesn't cover my entire face but its a great mask. I tried the caviar one this time. I have the collagen ones as well but these have better reviews. They seem to work effectively, for a nice glow and self pamper session.
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Reviewed in the United States on May 5, 2026
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Verified Purchase
Mom who does everything
Port Orchard, US
★★★★★ 5
My Favorite Mask
Scent: Collagen, Size: 4 Count (Pack of 1)
I’ve been really impressed with this Bio-Collagen hydrogel mask! It feels incredibly cooling and soothing on the skin, especially after a long day. The overnight wear is a huge plus—you wake up with your skin feeling noticeably more hydrated, plump, and smooth. It doesn’t feel heavy or sticky, and it stays in place better than most sheet masks. After a few uses, I’ve noticed my skin looks more refreshed and even, and my pores appear a bit more minimized. It’s a great option when your skin needs a little extra boost or before an event when you want that “glow.”
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Reviewed in the United States on May 5, 2026

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