SKU: 99208699615

Lymphocyte antigen 75/CD205 Recombinant Rabbit mAb (S-2707-25)

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Description

Lymphocyte antigen 75/CD205 Recombinant Rabbit mAb (S-2707-25)Product Specification Host Rabbit Antigen CD205 Synonyms Lymphocyte antigen 75; Ly 75; C type lectin domain family 13 member B; DEC 205; gp200 MR6; CLEC13B; LY75 Immunogen Recombinant Protein Location Membrane Accession O60449 Clone Number S 2707 25 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Positive Sample THP 1, Daudi Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance

Product Specification


Host Rabbit
Antigen CD205
Synonyms Lymphocyte antigen 75; Ly-75; C-type lectin domain family 13 member B; DEC-205; gp200-MR6; CLEC13B; LY75
Immunogen Recombinant Protein
Location Membrane
Accession O60449
Clone Number S-2707-25
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IHC-P
Reactivity Hu
Positive Sample THP-1, Daudi
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu
IHC-P 1:1000 Hu

Background

CD205, also known as DEC205 or LY75, is a ~205 kDa type I transmembrane glycoprotein belonging to the macrophage mannose receptor family of C-type lectins; it contains an N-terminal cysteine-rich domain, a fibronectin type II repeat, ten tandem C-type lectin-like carbohydrate-recognition domains, a single transmembrane segment and a short cytoplasmic tail harboring the tyrosine-based “FERN” and “DIEEV” endosomal sorting motifs that drive constitutive clathrin-mediated internalization and recycling to late endosomes/MHC class II compartments. Predominantly expressed on CD8α⁺ dendritic cells, thymic epithelial cells and certain B subsets, CD205 functions as a pattern-recognition receptor that binds apoptotic/necrotic cells, selected glycoproteins and CpG-rich nucleic acids, enabling efficient capture, processing and cross-presentation of antigens for initiation of CD8⁺ T-cell immunity; this property has made it a premier target for receptor-directed vaccination strategies in which antigens are fused to anti-CD205 antibodies to elicit potent, antigen-specific tolerance or protective responses. In addition, CD205 participates in peripheral T-cell deletion, central tolerance through negative selection in the thymus, and has been implicated in autoimmune diseases, tumor immunosurveillance and metastasis, with its expression levels correlating with prognosis in several cancers, thereby serving as both a biomarker and a therapeutic gateway in immunotherapy.

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Exchange/Return Notes
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SKU: 99208699615

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4.6 ★★★★★
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Lindsay Eure
Omaha, US
★★★★★ 5
Nice but better on tall men
We ordered this for a show. Our actor is 5’9” and the sleeves and legs are too long as well as the body of the tunic.I believe we ordered a medium. The waist fit and we could not go any smaller. In another review I have an actor who is 6’5” and very thin in the same size and it fits him well.
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Reviewed in the United States on August 18, 2022
K
Verified Purchase
Katie Williams
Bozeman, US
★★★★★ 5
Cute Comfy Cultured 💕
Color: Burgundy With Gold, Size: Small, Color: Burgundy With Gold, Size: Small
I ordered all my boys the men's sizes because I needed the burgundy gold tones to match my dress. All their outfits were longer then need but was expected because they're not men! My 8yr old wore men's small, my 10yr old wore men's medium, 13yr old wore men's large and our taller 12yr old wore XL. They color was deep, the gold is a print not embroidery but they all were handsome and comfortable 💕
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Reviewed in the United States on March 7, 2022
K
Verified Purchase
Karla C
Houston, US
★★★★★ 5
pants were a little long but easy to fix
Size: Small, Color: Dark Black, Size: Small, Color: Dark Black
No regrets whatsoever about getting this tuxedo the quality was great the material felt very nice and it looks high quality the pants were a tiny bit too long but easy to get fixed and is wrinkle resistant honestly this product is worth every penny
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Reviewed in the United States on November 6, 2025
A
Verified Purchase
Amazon Customer
Alexandria, US
★★★★★ 5
Was good for the price .
Size: 3X-Large, Color: Dark Black
The tux fit correctly by using the size chart on the product window I used.
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Reviewed in the United States on May 18, 2026
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Verified Purchase
Hodari
Birmingham, US
★★★★★ 5
Excellent quality
Size: Large, Color: Purple
Perfect tuxedo to use for many functions. Got it about 2 years ago and have used it probably twice for galas as well as awards programs. Fits to size and didn’t break the bank. Texture is good and it is easy to pair with anything as well as is reusable.
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Reviewed in the United States on January 20, 2026

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