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Description
CD3 epsilon&CD3 delta Heterodimer Fc, His Tag&Fc, Flag Tag Protein, HumanProduct Specification Species Human Synonyms CD3 epsilon&CD3 delta, CD3E & CD3D Accession P07766 1(CD3E)P04234 1(CD3D) Amino Acid Sequence Asp 23 Asp 126 (CD3E) with hIgG1 Fc Tag at the C Terminus, followed by His Tag Phe 22 Ala 105 (CD3D) with hIgG1 Fc Tag at the C Terminus, followed by Flag Tag Expression System HEK293 Molecular Weight 40 55kDa (Reducing) Purity 95% by SDS PAGE & HPLC Conjugation Unconjugated Tag His Tag, Flag Tag, Human IgG1 Fc
Product Specification
| Species | Human |
| Synonyms | CD3 epsilon&CD3 delta, CD3E & CD3D |
| Accession | P07766-1(CD3E)、P04234-1(CD3D) |
| Amino Acid Sequence | Asp 23 - Asp 126 (CD3E) with hIgG1 Fc Tag at the C-Terminus, followed by His Tag |
| Expression System | HEK293 |
| Molecular Weight | 40-55kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & HPLC |
| Conjugation | Unconjugated |
| Tag | His Tag, Flag Tag, Human IgG1 Fc |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | 1. Tuning TCR complex recruitment to the T cell antigen coupler (TAC) enhances TAC-T cell function. Sci Rep. 2025 Feb 25;15(1):6769. |
Background
T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
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