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Description
Phospho-Vimentin (Ser56) Recombinant Rabbit mAb (S-2135-5)Product Specification Host Rabbit Antigen Phospho Vimentin (Ser56) Synonyms Vimentin; VIM Immunogen Synthetic Peptide Location Cytoplasm, Cytoskeleton, Cell membrane Accession P08670 Clone Number S 2135 5 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Predicted Reactivity AfGrMk, Cz, Pg, Dg Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0.
Product Specification
| Host | Rabbit |
| Antigen | Phospho-Vimentin (Ser56) |
| Synonyms | Vimentin; VIM |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Cytoskeleton, Cell membrane |
| Accession | P08670 |
| Clone Number | S-2135-5 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu |
| Predicted Reactivity | AfGrMk, Cz, Pg, Dg |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| Dot Blot | 1:1000 | |
| WB | 1:1000 | Hu |
Background
Phospho-Vimentin (Ser56) is a phosphorylated form of the vimentin protein, specifically at serine residue 56. Vimentin is a type of intermediate filament protein that plays a crucial role in maintaining cell integrity and providing mechanical support to cells. When phosphorylated at Ser56, it often indicates involvement in cellular processes such as cell migration, adhesion, and the epithelial-mesenchymal transition (EMT). This phosphorylation can be a key marker in various biological contexts, including cancer progression, where it may be associated with the enhanced motility and invasive potential of tumor cells.
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