SKU: 93320574391

CD140b/PDGFRB His Tag Protein, Human

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Description

CD140b/PDGFRB His Tag Protein, HumanProduct Specification Species Human Antigen CD140b PDGFRB Synonyms J03278, M21616, JTK12, pdgf r Accession P09619 Amino Acid Sequence Leu33 Val532, with C terminal 10*His

Product Specification


Species Human
Antigen CD140b/PDGFRB
Synonyms J03278, M21616, JTK12, pdgf-r-β
Accession P09619
Amino Acid Sequence

Leu33-Val532, with C-terminal 10*His LVVTPPGPELVLNVSSTFVLTCSGSAPVVWERMSQEPPQEMAKAQDGTFSSVLTLTNLTGLDTGEYFCTHNDSRGLETDERKRLYIFVPDPTVGFLPNDAEELFIFLTEITEITIPCRVTDPQLVVTLHEKKGDVALPVPYDHQRGFSGIFEDRSYICKTTIGDREVDSDAYYVYRLQVSSINVSVNAVQTVVRQGENITLMCIVIGNEVVNFEWTYPRKESGRLVEPVTDFLLDMPYHIRSILHIPSAELEDSGTYTCNVTESVNDHQDEKAINITVVESGYVRLLGEVGTLQFAELHRSRTLQVVFEAYPPPTVLWFKDNRTLGDSSAGEIALSTRNVSETRYVSELTLVRVKVAEAGHYTMRAFHEDAEVQLSFQLQINVPVRVLELSESHPDSGEQTVRCRGRGMPQPNIIWSACRDLKRCPRELPPTLLGNSSEEESQLETNVTYWEEEQEFEVVSTLRLQHVDRPLSVRCTLRNAVGQDTQEVIVVPHSLPFKVGGGSGGGSHHHHHHHHHH

Expression System HEK293
Molecular Weight 75-95kDa
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1. RAMESH PERIASAMY, SALLY L. ELSHAER, RAJASHEKHAR GANGARAJU. CD140b (PDGFRp) Signaling in Adipose-Derived Stem Cells Mediates Angiogenic Behavior of Retinal Endothelial Cells.[J]. Regenerative engineering and translational medicine,2019,5(1):1-9.

Background

Human platelet-derived growth factor receptor, beta polypeptide (PDGFRB) is receptor that binds specifically to PDGFB. It is characterized by the presence of five immunoglobulin- like domains in their extracellular region and a split kinase domain in their intracellular region. The extracellular domain of human PDGF R beta contains 4 disulfide bonds and shares a 79% sequence identity with mouse and rat PDGF R beta. It is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor (PDGF) family. Recombinant soluble PDGFRB binds PDGF with high affinity and is potent PDGF antagonist.Many cell types, including fibroblasts and smooth muscle cells, express both the alpha and beta receptors.

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SKU: 93320574391

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