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Description
Feline Leukemia Virus p27 Recombinant Rabbit mAb (SDT-597-56)Product Specification Host Rabbit Antigen Feline Leukemia Virus p27 Synonyms FeLV Immunogen Recombinant Protein Accession P10262 Clone Number SDT 597 56 Antibody Type Recombinant mAb Isotype IgG Application Sandwich ELISA Reactivity FELINE Cross Reactivity Does not recognize FeLV p24 Purification Protein A Concentration 2 mg ml Purity >95% by HPLC Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4, 0. 03% Proclin 300
Product Specification
| Host | Rabbit |
| Antigen | Feline Leukemia Virus p27 |
| Synonyms | FeLV |
| Immunogen | Recombinant Protein |
| Accession | P10262 |
| Clone Number | SDT-597-56 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | FELINE |
| Cross Reactivity | Does not recognize FeLV p24 |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Purity | >95% by HPLC |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| Sandwich ELISA | N/A |
Background
The feline leukemia virus (FeLV) is the causative agent of the most important fatal infectious disease complex of domestic cats. FeLV is transmitted mostly by direct contact via saliva, nasal secretions, and milk by mutual grooming or occasionally by bites. It can also be transmitted indirectly via contact with faeces from FeLV-viremic shedders. Transmission from mother to offspring also occurs occasionally. Young kittens are especially susceptible to FeLV infection while with increasing age cats become more resistant to infection. The majority of in-practice tests for FeLV detect viral antigen (capsid protein p27) in blood, plasma or serum. P27 is the most abundant viral protein in the plasma of viraemic cats as a diagnostic marker. FeLV is the most common cause of cancer in cats, may cause various blood disorders, and may lead to a state of immune deficiency that hinders a cat's ability to protect itself against other infections. After being infected with FeLV, common bacteria, viruses, protozoa, and fungi all can cause severe illness in cats.
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